Matthias Rief
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Explore the profile of Matthias Rief including associated specialties, affiliations and a list of published articles.
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139
Citations
3405
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Recent Articles
11.
Kofoed K, Bosserdt M, Maurovich-Horvat P, Rieckmann N, Benedek T, Donnelly P, et al.
BMJ
. 2022 Oct;
379:e071133.
PMID: 36261169
Objective: To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women and men with stable chest pain suspected to be caused by coronary artery disease. Design:...
12.
Singh A, Rief M, Zoldak G
Biophys J
. 2022 Oct;
121(23):4729-4739.
PMID: 36196054
Protein allostery requires a communication channel for functional regulation between distal sites within a protein. In the molecular chaperone Hsp70, a two-domain enzyme, the ATP/ADP status of an N-terminal nucleotide-binding...
13.
Tych K, Rief M
Methods Mol Biol
. 2022 Sep;
2478:401-425.
PMID: 36063329
The heat shock protein 90 (Hsp90) family of chaperones are well-known, highly important components of the cellular systems which regulate protein homeostasis. Essential in eukaryotes, Hsp90s is also found in...
14.
Jones A, Walbrun A, Falleroni F, Rief M, Sattler M
J Mol Biol
. 2022 Jun;
434(18):167705.
PMID: 35760371
MicroRNAs (miRNAs) are small, noncoding RNAs that mediate post-transcriptional downregulation of specific target genes. These transcripts are the products of a two-step processing pathway; primary miRNAs (pri-miRNAs) are processed by...
15.
Moessmer P, Suren T, Majdic U, Dahiya V, Rutz D, Buchner J, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(15):e2119076119.
PMID: 35377810
The glucocorticoid receptor (GR) is an important transcription factor and drug target linked to a variety of biological functions and diseases. It is one of the most stringent physiological clients...
16.
Synakewicz M, Eapen R, Perez-Riba A, Rowling P, Bauer D, Weissl A, et al.
ACS Nano
. 2022 Mar;
16(3):3895-3905.
PMID: 35258937
Tandem-repeat proteins comprise small secondary structure motifs that stack to form one-dimensional arrays with distinctive mechanical properties that are proposed to direct their cellular functions. Here, we use single-molecule optical...
17.
Maurovich-Horvat P, Bosserdt M, Kofoed K, Rieckmann N, Benedek T, Donnelly P, et al.
N Engl J Med
. 2022 Mar;
386(17):1591-1602.
PMID: 35240010
Background: In the diagnosis of obstructive coronary artery disease (CAD), computed tomography (CT) is an accurate, noninvasive alternative to invasive coronary angiography (ICA). However, the comparative effectiveness of CT and...
18.
Dahiya V, Rutz D, Moessmer P, Muhlhofer M, Lawatscheck J, Rief M, et al.
Mol Cell
. 2022 Feb;
82(8):1543-1556.e6.
PMID: 35176233
Folding of stringent clients requires transfer from Hsp70 to Hsp90. The co-chaperone Hop physically connects the chaperone machineries. Here, we define its role from the remodeling of Hsp70/40-client complexes to...
19.
Preuss D, Garcia G, Laule M, Dewey M, Rief M
Eur Radiol Exp
. 2022 Jan;
6(1):5.
PMID: 35099638
Background: Multisegment reconstruction (MSR) was introduced to shorten the temporal reconstruction window of computed tomography (CT) and thereby reduce motion artefacts. We investigated whether MSR of myocardial CT perfusion (CTP)...
20.
Sengupta A, Rognoni L, Merkel U, Zoldak G, Rief M
J Phys Chem B
. 2021 Jul;
125(31):8712-8721.
PMID: 34279937
Prolyl isomerization is recognized as one of the key regulatory mechanisms, which plays a crucial role in cell signaling, ion channel gating, phage virus infection, and molecular timing. This isomerization...