Matthias Lauth
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Explore the profile of Matthias Lauth including associated specialties, affiliations and a list of published articles.
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57
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2308
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Recent Articles
1.
Ems M, Brichkina A, Lauth M
Oncogene
. 2025 Jan;
44(6):341-347.
PMID: 39863750
The development of resistance remains one of the biggest challenges in clinical cancer patient care and it comprises all treatment modalities from chemotherapy to targeted or immune therapy. In solid...
2.
Gao Y, Zandieh K, Zhao K, Khizanishvili N, Di Fazio P, Yu X, et al.
Cell Oncol (Dordr)
. 2024 Oct;
PMID: 39412616
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers and several studies demonstrate that STAT3 has critical roles throughout the course of PDAC pathogenesis. Methods: TCGA, microarray,...
3.
Hanze J, Mengen L, Mernberger M, Tiwari D, Plagge T, Nist A, et al.
Radiat Oncol
. 2024 Jul;
19(1):85.
PMID: 38956684
Background: Radiotherapy is essential in the treatment of prostate cancer. An alternative to conventional photon radiotherapy is the application of carbon ions, which provide a superior intratumoral dose distribution and...
4.
Alashkar Alhamwe B, Ponath V, Alhamdan F, Dorsam B, Landwehr C, Linder M, et al.
Cell Mol Immunol
. 2024 Jun;
21(8):918-931.
PMID: 38942797
Recent studies reveal a critical role of tumor cell-released extracellular vesicles (EVs) in pancreatic cancer (PC) progression. However, driver genes that direct EV function, the EV-recipient cells, and their cellular...
5.
Karimova A, Ketkar A, Suezov R, Khalitova A, Gomzikova M, Mukhamedshina Y, et al.
FASEB J
. 2024 Jun;
38(13):e23730.
PMID: 38900063
Tumor-associated macrophages (TAMs) are integral components of the tumor microenvironment. They are involved in various aspects of tumor cell biology, driving pathological processes such as tumor cell proliferation, metastasis, immunosuppression,...
6.
Brichkina A, Ems M, Suezov R, Singh R, Lutz V, Picard F, et al.
Gut
. 2024 Jun;
73(10):1684-1701.
PMID: 38834297
Objective: Highly malignant pancreatic ductal adenocarcinoma (PDAC) is characterised by an abundant immunosuppressive and fibrotic tumour microenvironment (TME). Future therapeutic attempts will therefore demand the targeting of tumours and stromal...
7.
Brichkina A, Polo P, Sharma S, Visestamkul N, Lauth M
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37174079
Pancreatic cancer represents one of the most desmoplastic malignancies and is characterized by an extensive deposition of extracellular matrix. The latter is provided by activated cancer-associated fibroblasts (CAFs), which are...
8.
Luu M, Schutz B, Lauth M, Visekruna A
Cancers (Basel)
. 2023 Mar;
15(5).
PMID: 36900377
Prevention of the effectiveness of anti-tumor immune responses is one of the canonical cancer hallmarks. The competition for crucial nutrients within the tumor microenvironment (TME) between cancer cells and immune...
9.
Picard F, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, et al.
Gut
. 2023 Feb;
72(8):1510-1522.
PMID: 36759154
Objective: Pancreatic ductal adenocarcinoma (PDAC) is characterised by an abundant desmoplastic stroma composed of cancer-associated fibroblasts (CAF) and interspersed immune cells. A non-canonical CD8 T-cell subpopulation producing IL-17A (Tc17) promotes...
10.
Koeniger A, Polo P, Brichkina A, Finkernagel F, Visekruna A, Nist A, et al.
NAR Cancer
. 2023 Feb;
5(1):zcad007.
PMID: 36755960
Transcriptional cancer subtypes which correlate with traits such as tumor growth, drug sensitivity or the chances of relapse and metastasis, have been described for several malignancies. The core regulatory circuits...