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Matthias E Futschik

Explore the profile of Matthias E Futschik including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 2232
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Recent Articles
11.
Djeghloul D, Dimond A, Cheriyamkunnel S, Kramer H, Patel B, Brown K, et al.
Nat Struct Mol Biol . 2023 Mar; 30(4):489-501. PMID: 36941433
Recent studies have shown that repressive chromatin machinery, including DNA methyltransferases and polycomb repressor complexes, binds to chromosomes throughout mitosis and their depletion results in increased chromosome size. In the...
12.
Bonet F, Anez S, Inacio J, Futschik M, Belo J
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36293499
The epicardium is a single cell layer of mesothelial cells that plays a critical role during heart development contributing to different cardiac cell types of the developing heart through epithelial-to-mesenchymal...
13.
Francis C, Futschik M, Huang J, Bai W, Sargurupremraj M, Teumer A, et al.
Nat Commun . 2022 Aug; 13(1):4505. PMID: 35922433
Aortic dimensions and distensibility are key risk factors for aortic aneurysms and dissections, as well as for other cardiovascular and cerebrovascular diseases. We present genome-wide associations of ascending and descending...
14.
Kuiper M, Bonello J, Fernandez-Breis J, Bucher P, Futschik M, Gaudet P, et al.
Biochim Biophys Acta Gene Regul Mech . 2021 Nov; 1865(1):194768. PMID: 34757206
As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability...
15.
Riediger M, Hernandez-Prieto M, Song K, Hess W, Futschik M
DNA Res . 2021 Oct; 28(6). PMID: 34672328
The Ferric uptake regulator (Fur) is crucial to both pathogenic and non-pathogenic bacteria for the maintenance of iron homeostasis as well as the defence against reactive oxygen species. Based on...
16.
Machado R, Sachinidis A, Futschik M
Cells . 2021 Sep; 10(9). PMID: 34572125
In vitro differentiation of embryonic stem cells (ESCs) provides a convenient basis for the study of microRNA-based gene regulation that is relevant for early cardiogenic processes. However, to which degree...
17.
Giner-Lamia J, Hernandez-Prieto M, Futschik M
Bio Protoc . 2021 Jul; 8(12):e2895. PMID: 34286004
Nitrogen is an essential nutrient for all living organisms. In cyanobacteria, a group of oxygenic photosynthetic bacteria, nitrogen homeostasis is maintained by an intricate regulatory network around the transcription factor...
18.
Inacio J, von Gilsa Lopes J, Silva A, Cristo F, Marques S, Futschik M, et al.
Front Cell Dev Biol . 2021 Apr; 9:629430. PMID: 33928078
Deciphering the clues of a regenerative mechanism for the mammalian adult heart would save millions of lives in the near future. Heart failure due to cardiomyocyte loss is still one...
19.
Dunn J, Lenis V, Hilton D, Warta R, Herold-Mende C, Hanemann C, et al.
Cancers (Basel) . 2020 Nov; 12(11). PMID: 33167358
Meningioma are the most frequent primary intracranial tumour. Management of aggressive meningioma is complex, and development of effective biomarkers or pharmacological interventions is hampered by an incomplete knowledge of molecular...
20.
Krynicka V, Georg J, Jackson P, Dickman M, Hunter C, Futschik M, et al.
Plant Cell . 2019 Oct; 31(12):2912-2928. PMID: 31615847
The membrane-embedded FtsH proteases found in bacteria, chloroplasts, and mitochondria are involved in diverse cellular processes including protein quality control and regulation. The genome of the model cyanobacterium sp PCC...