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Rui S R Machado

Explore the profile of Rui S R Machado including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 156
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Recent Articles
1.
Santos J, Mendes-Silva L, Afonso V, Martins G, Machado R, Lopes J, et al.
Cell Death Dis . 2019 Aug; 10(8):582. PMID: 31378782
Mutations and inadequate methylation profiles of CITED2 are associated with human congenital heart disease (CHD). In mouse, Cited2 is necessary for embryogenesis, particularly for heart development, and its depletion in...
2.
Sabour D, Machado R, Pinto J, Rohani S, Sahito R, Hescheler J, et al.
Mol Ther Nucleic Acids . 2018 Sep; 12:158-173. PMID: 30195755
Heart development is a complex process, tightly regulated by numerous molecular mechanisms. Key components of the regulatory network underlying heart development are transcription factors (TFs) and microRNAs (miRNAs), yet limited...
3.
Pinto J, Machado R, Magno R, Oliveira D, Machado S, Andrade R, et al.
Nucleic Acids Res . 2017 Oct; 46(D1):D788-D793. PMID: 29045725
Transcriptomic data have become a fundamental resource for stem cell (SC) biologists as well as for a wider research audience studying SC-related processes such as aging, embryonic development and prevalent...
4.
Pinto J, Kalathur R, Oliveira D, Barata T, Machado R, Machado S, et al.
Nucleic Acids Res . 2015 May; 43(W1):W72-7. PMID: 26007653
Stem cells present unique regenerative abilities, offering great potential for treatment of prevalent pathologies such as diabetes, neurodegenerative and heart diseases. Various research groups dedicated significant effort to identify sets...
5.
Pinto J, Machado R, Xavier J, Futschik M
Front Genet . 2014 Jun; 5:160. PMID: 24926314
The study of molecular networks has recently moved into the limelight of biomedical research. While it has certainly provided us with plenty of new insights into cellular mechanisms, the challenge...
6.
Pinto J, Kalathur R, Machado R, Xavier J, Braganca J, Futschik M
Nucleic Acids Res . 2014 May; 42(Web Server issue):W154-60. PMID: 24852251
Stem cells are characterized by their potential for self-renewal and their capacity to differentiate into mature cells. These two key features emerge through the interplay of various factors within complex...
7.
Kalathur R, Pinto J, Hernandez-Prieto M, Machado R, Almeida D, Chaurasia G, et al.
Nucleic Acids Res . 2013 Nov; 42(Database issue):D408-14. PMID: 24214987
Unified Human Interactome (UniHI) (http://www.unihi.org) is a database for retrieval, analysis and visualization of human molecular interaction networks. Its primary aim is to provide a comprehensive and easy-to-use platform for...