Matthias Drum
Overview
Explore the profile of Matthias Drum including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
30
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Recent Articles
1.
Senst A, Caliebe A, Drum M, Cossu C, Zieger M, Scheurer E, et al.
Forensic Sci Int Genet
. 2022 Oct;
62:102790.
PMID: 36272213
Successful DNA-based identification of altered human remains relies on the condition of the corpses and varies between tissue types. Therefore, the aim of this prospective multicenter study was to generate...
2.
Aschenbrenner J, Drum M, Topal H, Wieland M, Marx A
Angew Chem Int Ed Engl
. 2014 Jun;
53(31):8154-8.
PMID: 24923910
The epigenetic control of genes by the methylation of cytosine resulting in 5-methylcytosine (5mC) has fundamental implications for human development and disease. Analysis of alterations in DNA methylation patterns is...
3.
Drum M, Kranaster R, Ewald C, Blasczyk R, Marx A
PLoS One
. 2014 May;
9(5):e96640.
PMID: 24800860
The selectivity of DNA polymerases is crucial for many applications. For example, high discrimination between the extension of matched versus mismatched primer termini is desired for the detection of a...
4.
Kranaster R, Drum M, Engel N, Weidmann M, Hufert F, Marx A
Biotechnol J
. 2010 Jan;
5(2):224-31.
PMID: 20108275
We describe the cloning and characterization of a mutated thermostable DNA polymerase from Thermus aquaticus (Taq) that exhibits an increased reverse transcriptase activity and is therefore designated for one-step PCR...