Matthew W Mitchell
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Explore the profile of Matthew W Mitchell including associated specialties, affiliations and a list of published articles.
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26
Citations
1409
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Recent Articles
1.
Pozner T, Grandizio C, Mitchell M, Turan N, Scheinfeldt L
Stem Cells Int
. 2025 Jan;
2025:2223645.
PMID: 39850337
Since their discovery, human induced pluripotent stem cells (hiPSCs) have been instrumental in biomedical research, particularly in the fields of disease modelling, drug screening and regenerative therapies. Their use has...
2.
Gaedigk A, Boone E, Turner A, van Schaik R, Chernova D, Wang W, et al.
J Mol Diagn
. 2023 Jun;
25(9):655-664.
PMID: 37354993
Pharmacogenetic testing for CYP3A4 is increasingly provided by clinical and research laboratories; however, only a limited number of quality control and reference materials are currently available for many of the...
3.
Liao W, Asri M, Ebler J, Doerr D, Haukness M, Hickey G, et al.
Nature
. 2023 May;
617(7960):312-324.
PMID: 37165242
Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individuals. These...
4.
Dwivedi-Yu J, Oppler Z, Mitchell M, Song Y, Brisson D
PLoS Comput Biol
. 2023 Apr;
19(4):e1010137.
PMID: 37068103
Addressing many of the major outstanding questions in the fields of microbial evolution and pathogenesis will require analyses of populations of microbial genomes. Although population genomic studies provide the analytical...
5.
Pilling O, Reis-Cunha J, Grace C, Berry A, Mitchell M, Yu J, et al.
PLoS Pathog
. 2023 Mar;
19(3):e1011230.
PMID: 36940219
In Brazil, Leishmania braziliensis is the main causative agent of the neglected tropical disease, cutaneous leishmaniasis (CL). CL presents on a spectrum of disease severity with a high rate of...
6.
Jarvis E, Formenti G, Rhie A, Guarracino A, Yang C, Wood J, et al.
Nature
. 2022 Oct;
611(7936):519-531.
PMID: 36261518
The current human reference genome, GRCh38, represents over 20 years of effort to generate a high-quality assembly, which has benefitted society. However, it still has many gaps and errors, and...
7.
Pratt V, Wang W, Boone E, Broeckel U, Cody N, Edelmann L, et al.
J Mol Diagn
. 2022 Aug;
24(10):1079-1088.
PMID: 35931342
Pharmacogenetic testing is increasingly provided by clinical and research laboratories; however, only a limited number of quality control and reference materials are currently available for many of the TPMT and...
8.
Mitchell M, Grandizio C, Turan N, Requesens D
Stem Cell Res
. 2022 Jun;
63:102833.
PMID: 35700637
Vici syndrome is a rare, congenital disorder that affects multiple systems and is caused by mutations in the EPG5 gene that encodes for ectopic P-granules autophagy protein 5 (EPG5). The...
9.
Abwe E, Morgan B, Tchiengue B, Kentatchime F, Doudja R, Ketchen M, et al.
Ecol Evol
. 2019 Feb;
9(3):1489-1500.
PMID: 30805176
Ecological niche models (ENMs) are often used to predict species distribution patterns from datasets that describe abiotic and biotic factors at coarse spatial scales. Ground-truthing ENMs provide important information about...
10.
Cohen I, Cirulli E, Mitchell M, Jonsson T, Yu J, Shah N, et al.
EBioMedicine
. 2018 Feb;
28:316-323.
PMID: 29398597
Background: Acetaminophen (paracetamol) is one of the most common medications used for management of pain in the world. There is lack of consensus about the mechanism of action, and concern...