Matthew W Freyer
Overview
Explore the profile of Matthew W Freyer including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
206
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Laroche C, Li J, Freyer M, Kerwin S
J Org Chem
. 2008 Jul;
73(16):6462-5.
PMID: 18646827
A cross-coupling reaction of imidazoles with bromoalkynes in the presence of a catalytic amount of CuI is reported. This protocol allows an access to novel N-(1-alkynyl)imidazoles in moderate to good...
2.
Cashman D, Buscaglia R, Freyer M, Dettler J, Hurley L, Lewis E
J Mol Model
. 2007 Dec;
14(2):93-101.
PMID: 18087730
G-Quadruplex and i-Motif-forming sequences in the promoter regions of several oncogenes show promise as targets for the regulation of oncogenes. In this study, molecular models were created for the c-MYC...
3.
Freyer M, Lewis E
Methods Cell Biol
. 2007 Oct;
84:79-113.
PMID: 17964929
Isothermal titration calorimetry (ITC) is now routinely used to directly characterize the thermodynamics of biopolymer binding interactions and the kinetics of enzyme-catalyzed reactions. This is the result of improvements in...
4.
Smith R, Freyer M, Lewis E
J Virol Methods
. 2007 Mar;
142(1-2):151-8.
PMID: 17335913
To provide information for the development of new antiviral compounds that inhibit orthopoxviruses, further characterization of the kinetics and thermodynamics that underlie substrate utilization reactions of vaccinia virus thymidine kinase...
5.
Freyer M, Buscaglia R, Hollingsworth A, Ramos J, Blynn M, Pratt R, et al.
Biophys J
. 2007 Jan;
92(7):2516-22.
PMID: 17237207
Studies performed in our laboratory demonstrated the formation of two thermodynamically distinct complexes on binding of netropsin to a number of hairpin-forming DNA sequences containing AATT-binding regions. These two complexes...
6.
Freyer M, Buscaglia R, Kaplan K, Cashman D, Hurley L, Lewis E
Biophys J
. 2006 Dec;
92(6):2007-15.
PMID: 17172304
Regulation of the structural equilibrium of G-quadruplex-forming sequences located in the promoter regions of oncogenes by the binding of small molecules has shown potential as a new avenue for cancer...
7.
Freyer M, Buscaglia R, Nguyen B, Wilson W, Lewis E
Anal Biochem
. 2006 Jul;
355(2):259-66.
PMID: 16828700
Isothermal titration calorimetry (ITC), differential scanning calorimetry (DSC), and biosensor-surface plasmon resonance (SPR) are evaluated for their accuracy in determining equilibrium constants, ease of use, and range of application. Systems...