Matthew Stremlau
Overview
Explore the profile of Matthew Stremlau including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
3691
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Recent Articles
1.
Huang M, Stremlau M, Zavras J, Zivko C, Thomas A, Pietri P, et al.
Adv Pharmacol
. 2025 Feb;
102:65-101.
PMID: 39929585
Neutral sphingomyelinase 2 (nSMase2), encoded by the SMPD3 gene, is a pivotal enzyme in sphingolipid metabolism, hydrolyzing sphingomyelin to produce ceramide, a bioactive lipid involved in apoptosis, inflammation, membrane structure,...
2.
Edmunds K, Pandos A, Hoang I, Mamlouk G, Motovylyak A, Lose S, et al.
Alzheimers Dement (Amst)
. 2025 Jan;
17(1):e70062.
PMID: 39822291
Introduction: This study examined whether sex differences in verbal learning and memory (VLM) are mediated by plasma brain-derived neurotrophic factor (BDNF) expression. Methods: In a sample of = 201 participants...
3.
Nennig K, Murthy S, Maloney S, Shaw T, Sharobim M, Matkovic E, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012436.
PMID: 39196893
Viruses capable of causing persistent infection have developed sophisticated mechanisms for evading host immunity, and understanding these processes can reveal novel features of the host immune system. One such virus,...
4.
Botti-Lodovico Y, Nair P, Nosamiefan D, Stremlau M, Schaffner S, Agignoae S, et al.
Viruses
. 2021 Aug;
13(8).
PMID: 34452470
While investigating a signal of adaptive evolution in humans at the gene LARGE, we encountered an intriguing finding by Dr. Stefan Kunz that the gene plays a critical role in...
5.
Yoo S, Stremlau M, Pinto A, Woo H, Curtis O, van Praag H
Cells
. 2021 Aug;
10(7).
PMID: 34359946
Hyperlipidemia and hypertension are modifiable risk factors for cognitive decline. About 25% of adults over age 65 use both antihypertensives (AHTs) and statins to treat these conditions. Recent research in...
6.
Gaitan J, Moon H, Stremlau M, Dubal D, Cook D, Okonkwo O, et al.
Front Endocrinol (Lausanne)
. 2021 Jun;
12:660181.
PMID: 34093436
Increasing evidence indicates that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD). However, systemic biomarkers that can measure exercise effects on brain function...
7.
Kuhn J, Pan H, Chiu C, Stremlau M
Viruses
. 2020 Feb;
12(3).
PMID: 32106547
Rhabdoviruses are a large and ecologically diverse family of negative-sense RNA viruses (: ). These viruses are capable of infecting an unexpectedly wide variety of plants, vertebrates, and invertebrates distributed...
8.
Moon H, Javadi S, Stremlau M, Yoon K, Becker B, Kang S, et al.
Neuropharmacology
. 2018 Nov;
145(Pt A):123-130.
PMID: 30391731
Exercise has profound benefits for brain function in animals and humans. In rodents, voluntary wheel running increases the production of new neurons and upregulates neurotrophin levels in the hippocampus, as...
9.
Andersen K, Shapiro B, Matranga C, Sealfon R, Lin A, Moses L, et al.
Cell
. 2015 Aug;
162(4):738-50.
PMID: 26276630
The 2013-2015 West African epidemic of Ebola virus disease (EVD) reminds us of how little is known about biosafety level 4 viruses. Like Ebola virus, Lassa virus (LASV) can cause...
10.
Matranga C, Andersen K, Winnicki S, Busby M, Gladden A, Tewhey R, et al.
Genome Biol
. 2014 Nov;
15(11):519.
PMID: 25403361
We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples. Our...