Matthew S Rodeheffer
Overview
Explore the profile of Matthew S Rodeheffer including associated specialties, affiliations and a list of published articles.
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41
Citations
3170
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Recent Articles
1.
Heindel J, Alvarez J, Atlas E, Cave M, Chatzi V, Collier D, et al.
Am J Clin Nutr
. 2023 May;
118(1):329-337.
PMID: 37230178
On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors Strategies, an Environmental Health Sciences program, convened a scientific workshop of relevant stakeholders involved in obesity, toxicology, or obesogen...
2.
Speakman J, de Jong J, Sinha S, Westerterp K, Yamada Y, Sagayama H, et al.
Nat Metab
. 2023 Apr;
5(4):579-588.
PMID: 37100994
Obesity is caused by a prolonged positive energy balance. Whether reduced energy expenditure stemming from reduced activity levels contributes is debated. Here we show that in both sexes, total energy...
3.
Saavedra-Pena R, Taylor N, Flannery C, Rodeheffer M
Cell Rep
. 2023 Apr;
42(4):112390.
PMID: 37053070
White adipose tissue (WAT) distribution is sex dependent. Adipocyte hyperplasia contributes to WAT distribution in mice driven by cues in the tissue microenvironment, with females displaying hyperplasia in subcutaneous and...
4.
Varshney R, Das S, Trahan G, Farriester J, Mullen G, Kyere-Davies G, et al.
iScience
. 2023 Jan;
26(1):105750.
PMID: 36590177
Establishing metabolic programming begins during fetal and postnatal development, and early-life lipid exposures play a critical role during neonatal adipogenesis. We define how neonatal consumption of a low omega-6 to...
5.
Sebo Z, Rodeheffer M
Stem Cell Reports
. 2022 Apr;
17(5):1081-1088.
PMID: 35487210
Fat distribution is sexually dimorphic and is associated with metabolic disease risk. It is unknown if prepubertal sex-hormone signaling influences adult fat distribution. Here, we show that karyotypically male androgen-insensitive...
6.
Saavedra-Pena R, Taylor N, Rodeheffer M
J Mol Endocrinol
. 2022 Mar;
68(4):179-194.
PMID: 35244608
Sex hormones play a pivotal role in physiology and disease. Estrogen, the female sex hormone, has been long implicated in having protective roles against obesity. However, the direct impact of...
7.
Sebo Z, Rodeheffer M
Mol Metab
. 2020 Dec;
44:101141.
PMID: 33307216
Objective: Low testosterone in men (hypogonadism) is associated with obesity and type II diabetes. Testosterone replacement therapy has been shown to reverse these effects. However, the mechanisms by which testosterone...
8.
Tratwal J, Labella R, Bravenboer N, Kerckhofs G, Douni E, Scheller E, et al.
Front Endocrinol (Lausanne)
. 2020 Mar;
11:65.
PMID: 32180758
The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer)...
9.
Sebo Z, Rendina-Ruedy E, Ables G, Lindskog D, Rodeheffer M, Fazeli P, et al.
Endocr Rev
. 2019 May;
40(5):1187-1206.
PMID: 31127816
The presence of adipocytes in mammalian bone marrow (BM) has been recognized histologically for decades, yet, until recently, these cells have received little attention from the research community. Advancements in...
10.
Raajendiran A, Ooi G, Bayliss J, OBrien P, Schittenhelm R, Clark A, et al.
Cell Rep
. 2019 May;
27(5):1528-1540.e7.
PMID: 31042478
Adipocyte progenitor cells (APCs) provide the reservoir of regenerative cells to produce new adipocytes, although their identity in humans remains elusive. Using FACS analysis, gene expression profiling, and metabolic and...