Matthew S Lalonde
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Explore the profile of Matthew S Lalonde including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
141
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Recent Articles
1.
Tran R, Lalonde M, Sly K, Conboy J
J Phys Chem B
. 2019 May;
123(22):4673-4687.
PMID: 31084006
An extensive investigation into the initial association of HIV-1 Gag with lipid membranes was conducted with second harmonic generation. The roles of the lipid phase, phospholipid 1,2-dioleoyl- sn-glycero-3-phospho-(1-myo-inositol-4,5-bisphosphate) [PI(4,5)P], the...
2.
Mercenne G, Alam S, Arii J, Lalonde M, Sundquist W
Elife
. 2015 Jan;
4.
PMID: 25633977
Many retroviral Gag proteins contain PPXY late assembly domain motifs that recruit proteins of the NEDD4 E3 ubiquitin ligase family to facilitate virus release. Overexpression of NEDD4L can also stimulate...
3.
Santos A, Tebit D, Lalonde M, Abecasis A, Ratcliff A, Camacho R, et al.
Antimicrob Agents Chemother
. 2012 Feb;
56(5):2719-25.
PMID: 22330918
Hypersusceptibility (HS) to inhibition by different antiretroviral drugs (ARVs) among diverse HIV-infected individuals may be a misnomer because clinical response to treatment is evaluated in relation to subtype B infections...
4.
Lalonde M, Lobritz M, Ratcliff A, Chamanian M, Athanassiou Z, Tyagi M, et al.
PLoS Pathog
. 2011 Jun;
7(5):e1002038.
PMID: 21625572
The RNA response element TAR plays a critical role in HIV replication by providing a binding site for the recruitment of the viral transactivator protein Tat. Using a structure-guided approach,...
5.
Lalonde M, Arts E
PLoS One
. 2010 Nov;
5(11):e15476.
PMID: 21079742
Detection of low frequency single nucleotide polymorphisms (SNPs) has important implications in early screening for tumorgenesis, genetic disorders and pathogen drug resistance. Nucleic acid arrays are a powerful tool for...
6.
Soares E, Santos A, Gonzalez L, Lalonde M, Tebit D, Tanuri A, et al.
J Antimicrob Chemother
. 2009 Aug;
64(5):938-44.
PMID: 19710076
Objectives: Several drug resistance and secondary mutations have been described in HIV-1 viruses from patients undergoing antiretroviral therapy. In this study, we assessed the impact of the protease substitution T74S...
7.
Dudley D, Wentzel J, Lalonde M, Veazey R, Arts E
J Virol
. 2009 Mar;
83(10):5067-76.
PMID: 19279098
PSC-RANTES binds to CCR5, inhibits human immunodeficiency virus type 1 (HIV-1) entry, and has been shown as a vaginal microbicide to protect rhesus macaques from a simian-human immunodeficiency virus chimera...
8.
Troyer R, Lalonde M, Fraundorf E, Demers K, Kyeyune F, Mugyenyi P, et al.
AIDS Res Hum Retroviruses
. 2008 Feb;
24(2):235-50.
PMID: 18284323
This study explores the levels of NVP and AZT resistance mutations in untreated, NVP- or AZT-treated mother-infant pairs in Uganda. PCR-amplified reverse transcriptase (RT) gene fragments derived from PBMC samples...
9.
Lalonde M, Troyer R, Syed A, Bulime S, Demers K, Bajunirwe F, et al.
J Clin Microbiol
. 2007 Jun;
45(8):2604-15.
PMID: 17567789
This study has adapted the oligonucleotide ligation assay (OLA) to probe for low-level nevirapine (NVP) resistance mutations K103N and Y181C in the human immunodeficiency virus type 1 (HIV-1) population of...