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Matthew R Lee

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Articles 79
Citations 804
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Recent Articles
1.
Rodriguez-Villegas C, Perez-Santos I, Diaz P, Baldrich A, Lee M, Saldias G, et al.
Microorganisms . 2024 Oct; 12(10). PMID: 39458324
Over the recent decades, an apparent worldwide rise in Harmful Algae Blooms (HABs) has been observed due to the growing exploitation of the coastal environment, the exponential growth of monitoring...
2.
Montory J, Cubillos V, Chaparro O, Gebauer P, Lee M, Ramirez-Kuschel E, et al.
Antioxidants (Basel) . 2024 Jun; 13(6). PMID: 38929176
Azamethiphos is used in the salmon industry to treat sea lice and is subsequently discharged into the sea, which may affect non-target species (NTS). A rise in seawater temperature could...
3.
Lee M, Kady A, MacLean M, Stephenson A, Kwan T, Bowlby D, et al.
Prev Sci . 2023 Dec; 25(1):202. PMID: 38117381
No abstract available.
4.
Liu L, Malagu K, Haughan A, Khetarpal V, Stott A, Esmieu W, et al.
J Med Chem . 2023 Sep; 66(18):13205-13246. PMID: 37712656
Huntington's disease (HD) is caused by an expanded CAG trinucleotide repeat in exon 1 of the huntingtin () gene. We report the design of a series of pre-mRNA splicing modulators...
5.
Lee M, Kady A, MacLean M, Stephenson A, Kwan T, Bowlby D, et al.
Prev Sci . 2023 Jul; 24(5):887-900. PMID: 37507627
Older adult drinking poses a growing public health concern, especially given the ongoing aging of the United States population. As part of a larger lifespan developmental project contrasting predictors of...
6.
Montory J, Cubillos V, Lee M, Chaparro O, Gebauer P, Cumillaf J, et al.
Mar Environ Res . 2022 Dec; 183:105837. PMID: 36481714
The pesticide azamethiphos used by the salmon industry to treat sea lice, is applied as a bath and subsequently discharged into the sea. The effects of azamethiphos concentration (0, 15...
7.
Miranda C, Concha C, Godoy F, Lee M
Antibiotics (Basel) . 2022 Nov; 11(11). PMID: 36358142
The disposal of antibiotics in the aquatic environment favors the selection of bacteria exhibiting antibiotic resistance mechanisms. Quinolones are bactericidal antimicrobials extensively used in both human and animal medicine. Some...
8.
Lee M, Yeung E, Littlefield A, Stephenson A, Kady A, Kwan T, et al.
Dev Psychopathol . 2022 Oct; 36(1):1-11. PMID: 36286325
While prior literature has largely focused on marriage effects during young adulthood, it is less clear whether these effects are as strong in middle adulthood. Thus, we investigated age differences...
9.
Ladduwahetty T, Lee M, Maillard M, Cachope R, Todd D, Barnes M, et al.
J Med Chem . 2022 Jul; 65(14):9819-9845. PMID: 35816678
The Rho kinase (ROCK) pathway is implicated in the pathogenesis of several conditions, including neurological diseases. In Huntington's disease (HD), ROCK is implicated in mutant huntingtin (HTT) aggregation and neurotoxicity,...
10.
Liu L, Johnson P, Prime M, Khetarpal V, Lee M, Brown C, et al.
J Med Chem . 2021 Aug; 64(16):12003-12021. PMID: 34351166
The expanded polyglutamine-containing mutant huntingtin (mHTT) protein is implicated in neuronal degeneration of medium spiny neurons in Huntington's disease (HD) for which multiple therapeutic approaches are currently being evaluated to...