Matthew P Frost
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Explore the profile of Matthew P Frost including associated specialties, affiliations and a list of published articles.
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9
Citations
13
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Recent Articles
1.
Reis P, Holec S, Ezeiruaku C, Frost M, Brown C, Liu S, et al.
J Parkinsons Dis
. 2025 Feb;
14(8):1543-1558.
PMID: 39957201
Background: Multiple system atrophy (MSA) and Parkinson's disease (PD) are caused by misfolded α-synuclein spreading throughout the central nervous system. While familial PD is linked to several α-synuclein mutations, no...
2.
Reis P, Holec S, Ezeiruaku C, Frost M, Brown C, Liu S, et al.
bioRxiv
. 2024 Jul;
PMID: 39026799
Multiple system atrophy (MSA) and Parkinson's disease (PD) are caused by misfolded -synuclein spreading throughout the central nervous system. While familial PD is linked to several point mutations in -synuclein,...
3.
Lukomska A, Rheaume B, Frost M, Theune W, Xing J, Damania A, et al.
Exp Neurol
. 2024 Jun;
379:114877.
PMID: 38944331
In an attempt to repair injured central nervous system (CNS) nerves/tracts, immune cells are recruited into the injury site, but endogenous response in adult mammals is insufficient for promoting regeneration...
4.
Lukomska A, Frost M, Theune W, Xing J, Gupta M, Trakhtenberg E
Exp Neurol
. 2024 Feb;
375:114741.
PMID: 38395216
Nuclear factor erythroid 2 like (Nfe2l) gene family members 1-3 mediate cellular response to oxidative stress, including in the central nervous system (CNS). However, neuronal functions of Nfe2l3 are unknown....
5.
Lukomska A, Theune W, Frost M, Xing J, Kearney A, Trakhtenberg E
Neurosci Lett
. 2024 Jan;
823:137662.
PMID: 38286398
Numerous micro-RNAs (miRNAs) affect neurodevelopment and neuroprotection, but potential roles of many miRNAs in regulating these processes are still unknown. Here, we used the retinal ganglion cell (RGC) central nervous...
6.
Xing J, Theune W, Lukomska A, Frost M, Damania A, Trakhtenberg E
Exp Neurol
. 2023 Aug;
368:114510.
PMID: 37633482
Ribosomal proteins are involved in neurodevelopment and central nervous system (CNS) disease and injury. However, the roles of specific ribosomal protein subunits in developmental axon growth, and their potential as...
7.
Zeng Z, Tsay K, Vijayan V, Frost M, Prakash S, Quddus A, et al.
bioRxiv
. 2023 Jul;
PMID: 37502998
The discovery by cryo-electron microscopy (cryo-EM) that the neu-ropathological hallmarks of different tauopathies, including Alzheimer's disease, corticobasal degeneration (CBD), and progressive supranuclear palsy (PSP), are caused by unique misfolded conformations...
8.
Theune W, Frost M, Trakhtenberg E
Brain Res
. 2023 Apr;
1811:148377.
PMID: 37121423
Analysis of retinal ganglion cells (RGCs) by scRNA-seq is emerging as a state-of-the-art method for studying RGC biology and subtypes, as well as for studying the mechanisms of neuroprotection and...
9.
Lukomska A, Theune W, Xing J, Frost M, Damania A, Gupta M, et al.
Brain Res
. 2023 Apr;
1809:148368.
PMID: 37059258
Collapsin response mediator proteins (Crmps) play roles in neuronal development and axon growth. However, neuronal-specific roles of Crmp1, Crmp4, and Crmp5 in regeneration of injured central nervous system (CNS) axons...
10.
Delzell S, Nelson S, Frost M, Klingbeil M
Biochemistry
. 2022 Nov;
61(23):2751-2765.
PMID: 36399653
and related parasites contain an unusual catenated mitochondrial genome known as kinetoplast DNA (kDNA) composed of maxicircles and minicircles. The kDNA structure and replication mechanism are divergent and essential for...