Matthew M Halpert
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Explore the profile of Matthew M Halpert including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
268
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Recent Articles
1.
Halpert M, Burns B, Rosario S, Withers H, Trivedi A, Hofferek C, et al.
FASEB J
. 2024 May;
38(10):e23644.
PMID: 38738472
Tumors typically lack canonical danger signals required to activate adaptive immunity and also frequently employ substantial immunomodulatory mechanisms that downregulate adaptive responses and contribute to escape from immune surveillance. Given...
2.
Konduri V, Joseph S, Byrd T, Nawas Z, Vazquez-Perez J, Hofferek C, et al.
Sci Transl Med
. 2021 May;
13(592).
PMID: 33952672
In humans, the natural killer (NK) cell marker CD161 identifies several subsets of T cells, including a polyclonal CD8 αβ T cell receptor-expressing subset with characteristic specificity for tissue-localized viruses....
3.
Konduri V, Oyewole-Said D, Vazquez-Perez J, Weldon S, Halpert M, Levitt J, et al.
Front Immunol
. 2021 Feb;
11:613204.
PMID: 33597948
NK1.1 and its human homolog CD161 are expressed on NK cells, subsets of CD4 and CD8 T cells, and NKT cells. While the expression of NK1.1 is thought to be...
4.
Verrico C, Wesson S, Konduri V, Hofferek C, Vazquez-Perez J, Blair E, et al.
Pain
. 2020 Apr;
161(9):2191-2202.
PMID: 32345916
Over the last 2 decades, affirmative diagnoses of osteoarthritis (OA) in the United States have tripled due to increasing rates of obesity and an aging population. Hemp-derived cannabidiol (CBD) is...
5.
Halpert M, Konduri V, Liang D, Vazquez-Perez J, Hofferek C, Weldon S, et al.
FASEB J
. 2020 Apr;
34(6):8082-8101.
PMID: 32298026
Mammalian immune responses are initiated by "danger" signals--immutable molecular structures known as PAMPs. When detected by fixed, germline encoded receptors, pathogen-associated molecular pattern (PAMPs) subsequently inform the polarization of downstream...
6.
Liang D, Tian L, You R, Halpert M, Konduri V, Baig Y, et al.
Front Immunol
. 2018 Jan;
8:1801.
PMID: 29379495
Dendritic cells (DCs) must integrate a broad array of environmental cues to exact control over downstream immune responses including T polarization. The multienzyme aminoacyl-tRNA synthetase complex component AIMp1/p43 responds to...
7.
Konduri V, Halpert M, Liang D, Levitt J, Cruz-Chan J, Zhan B, et al.
Infect Immun
. 2017 Jul;
85(9).
PMID: 28674032
Chagas disease, caused by infection with the protozoan parasite , is a leading cause of heart disease ("chagasic cardiomyopathy") in Latin America, disproportionately affecting people in resource-poor areas. The efficacy...
8.
Konduri V, Li D, Halpert M, Liang D, Liang Z, Chen Y, et al.
Oncoimmunology
. 2016 Oct;
5(9):e1213933.
PMID: 27757308
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States, exhibiting a five-year overall survival (OS) of only 7% despite aggressive standard of care....
9.
Halpert M, Konduri V, Liang D, Chen Y, Wing J, Paust S, et al.
Stem Cells Dev
. 2016 Mar;
25(10):774-87.
PMID: 26979751
The remarkable functional plasticity of professional antigen-presenting cells (APCs) allows the adaptive immune system to respond specifically to an incredibly diverse array of potential pathogenic insults; nonetheless, the specific molecular...
10.
Konduri V, Decker W, Halpert M, Gilbert B, Safdar A
J Infect Dis
. 2013 Mar;
207(11):1764-72.
PMID: 23460750
Background: Cancer patients can exhibit negligible responses to prophylactic vaccinations, including influenza vaccination. To help address this issue, we developed in vitro and in vivo models of dendritic cell (DC)...