Matthew J Wargo
Overview
Explore the profile of Matthew J Wargo including associated specialties, affiliations and a list of published articles.
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68
Citations
1703
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Recent Articles
1.
DiGianivittorio P, Hinkel L, Mackinder J, Schutz K, Klein E, Wargo M
Microbiology (Reading)
. 2025 Jan;
171(1).
PMID: 39791474
Sphingoid bases, including sphingosine, are important components of the antimicrobial barrier at epithelial surfaces where they can cause growth inhibition and killing of susceptible bacteria. is a common opportunistic pathogen...
2.
DiGianivittorio P, Hinkel L, Mackinder J, Schutz K, Klein E, Wargo M
bioRxiv
. 2024 Sep;
PMID: 39282278
Sphingoid bases, including sphingosine, are important components of the antimicrobial barrier at epithelial surfaces where they can cause growth inhibition and killing of susceptible bacteria. is a common opportunistic pathogen...
3.
Mackinder J, Hinkel L, Schutz K, Eckstrom K, Fisher K, Wargo M
J Bacteriol
. 2024 Feb;
206(3):e0038223.
PMID: 38411048
Importance: PlcH is a secreted phospholipase C/sphingomyelinase that is important for the virulence of . Here, we show that sphingosine, which presents itself or as a product of sphingomyelinase and...
4.
Colgate E, Klopfer C, Dickson D, Lee B, Wargo M, Alam A, et al.
PLoS Comput Biol
. 2023 Nov;
19(11):e1011624.
PMID: 37992129
Despite significant progress in recent decades toward ameliorating the excess burden of diarrheal disease globally, childhood diarrhea remains a leading cause of morbidity and mortality in low-and-middle-income countries (LMICs). Recent...
5.
Legan T, Lavoie B, Norberg E, Ley I, Tack S, Tompkins T, et al.
Neurogastroenterol Motil
. 2023 Jun;
35(10):e14629.
PMID: 37357378
Background: An emerging strategy to treat symptoms of gastrointestinal (GI) dysmotility utilizes the administration of isolated bacteria. However, the underlying mechanisms of action of these bacterial agents are not well...
6.
Tristano J, Danforth D, Wargo M, Mintz K
Mol Oral Microbiol
. 2023 Mar;
38(3):237-250.
PMID: 36871155
Aggregatibacter actinomycetemcomitans is a gram-negative bacterium associated with periodontal disease and a variety of disseminated extra-oral infections. Tissue colonization is mediated by fimbriae and non-fimbriae adhesins resulting in the formation...
7.
Foote A, Schutz K, Zhao Z, DiGianivittorio P, Korwin-Mihavics B, LiPuma J, et al.
Microbiol Spectr
. 2023 Feb;
:e0410522.
PMID: 36744887
Ralstonia insidiosa and Chryseobacterium gleum are bacterial species commonly found in potable water systems, and these two species contribute to the robustness of biofilm formation in a model six-species community...
8.
Montgomery T, Eckstrom K, Lile K, Caldwell S, Heney E, Lahue K, et al.
Microbiome
. 2022 Nov;
10(1):198.
PMID: 36419205
Background: Dysregulation of gut microbiota-associated tryptophan metabolism has been observed in patients with multiple sclerosis. However, defining direct mechanistic links between this apparent metabolic rewiring and individual constituents of the...
9.
Hinkel L, Willsey G, Lenahan S, Eckstrom K, Schutz K, Wargo M
Microbiology (Reading)
. 2022 Mar;
168(3).
PMID: 35266867
Glutamine amidotransferase-1 domain-containing AraC-family transcriptional regulators (GATRs) are present in the genomes of many bacteria, including all species. The involvement of several characterized GATRs in amine-containing compound metabolism has been...
10.
Kokoszynska M, Ubags N, Bivona 3rd J, Ventrone S, Reed L, Dixon A, et al.
Physiol Rep
. 2021 Nov;
9(22):e15116.
PMID: 34822216
Obesity alters the risks and outcomes of inflammatory lung diseases. It is important to accurately recapitulate the obese state in animal models to understand these effects on the pathogenesis of...