Matthew J McGinley
Overview
Explore the profile of Matthew J McGinley including associated specialties, affiliations and a list of published articles.
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29
Citations
1986
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Recent Articles
1.
Quinones P, Pei M, Srivastava H, Cobo-Cuan A, Moran M, Kim B, et al.
J Neurosci
. 2025 Feb;
PMID: 39984203
The mammalian cochlea receives efferent feedback from the brain. Many functions for this feedback have been hypothesized, including on short timescales, such as mediating attentional states, and long timescales, such...
2.
Pehlivan D, Huang C, Harris H, Coquery C, Mahat A, Maletic-Savatic M, et al.
Ann Clin Transl Neurol
. 2025 Jan;
12(2):433-447.
PMID: 39838601
Objective: Rett syndrome (RTT) and MECP2 duplication syndrome (MDS) result from under- and overexpression of MECP2, respectively. Preclinical studies using genetic-based treatment showed robust phenotype recovery for both MDS and...
3.
Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
Jing J, Hu M, Ngodup T, Ma Q, Lau S, Ljungberg M, et al.
Nat Commun
. 2025 Jan;
16(1):489.
PMID: 39788966
The cochlear nuclear complex (CN), the starting point for all central auditory processing, encompasses a suite of neuronal cell types highly specialized for neural coding of acoustic signals. However, the...
4.
Mocchi M, Bartoli E, Magnotti J, de Gee J, Metzger B, Pascuzzi B, et al.
Sci Rep
. 2024 Dec;
14(1):30751.
PMID: 39730513
Alteration of responses to salient stimuli occurs in a wide range of brain disorders and may be rooted in pathophysiological brain state dynamics. Specifically, tonic and phasic modes of activity...
5.
Neyhart E, Zhou N, Munn B, Law R, Smith C, Mridha Z, et al.
Cell Rep
. 2024 Oct;
43(10):114808.
PMID: 39383037
Acetylcholine (ACh) is thought to play a role in driving the rapid, spontaneous brain-state transitions that occur during wakefulness; however, the spatiotemporal properties of cortical ACh activity during these state...
6.
Martin K, Papadoyannis E, Schiavo J, Fadaei S, Issa H, Song S, et al.
Nat Neurosci
. 2024 Sep;
27(11):2152-2166.
PMID: 39284963
Perception can be refined by experience, up to certain limits. It is unclear whether perceptual limits are absolute or could be partially overcome via enhanced neuromodulation and/or plasticity. Recent studies...
7.
de Gee J, Mridha Z, Hudson M, Shi Y, Ramsaywak H, Smith S, et al.
Curr Biol
. 2024 Aug;
34(18):4114-4128.e6.
PMID: 39151432
Arousal and motivation interact to profoundly influence behavior. For example, experience tells us that we have some capacity to control our arousal when appropriately motivated, such as staying awake while...
8.
Neyhart E, Zhou N, Munn B, Law R, Smith C, Mridha Z, et al.
bioRxiv
. 2024 Feb;
PMID: 38352527
Even under spontaneous conditions and in the absence of changing environmental demands, awake animals alternate between increased or decreased periods of alertness. These changes in brain state can occur rapidly,...
9.
Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
Jing J, Hu M, Ngodup T, Ma Q, Lau S, Ljungberg C, et al.
bioRxiv
. 2023 Jun;
PMID: 37293040
The cochlear nuclear complex (CN), the starting point for all central auditory processing, comprises a suite of neuronal cell types that are highly specialized for neural coding of acoustic signals,...
10.
McGinley M, Lee S
Neuron
. 2022 Sep;
110(17):2709-2712.
PMID: 36076336
Clinical applications of vagus nerve stimulation (VNS) are burgeoning, but mechanistic work lags behind. In this issue of Neuron, Bowles and colleagues show that VNS timed with positive reinforcement improves...