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Matthew J Killeen

Explore the profile of Matthew J Killeen including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 220
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Recent Articles
11.
Sabir I, Killeen M, Goddard C, Thomas G, Gray S, Grace A, et al.
J Physiol . 2007 Mar; 581(Pt 1):277-89. PMID: 17331992
Clinical hypokalaemia is associated with acquired electrocardiographic QT prolongation and arrhythmic activity initiated by premature ventricular depolarizations and suppressed by lidocaine (lignocaine). Nevertheless, regular (S1) pacing at a 125 ms...
12.
Sabir I, Fraser J, Killeen M, Grace A, Huang C
Pflugers Arch . 2007 Feb; 454(2):209-22. PMID: 17295037
The clinical effects of hypokalemia including action potential prolongation and arrhythmogenicity suppressible by lidocaine were reproduced in hypokalemic (3.0 mM K(+)) Langendorff-perfused murine hearts before and after exposure to lidocaine...
13.
Thomas G, Gurung I, Killeen M, Hakim P, Goddard C, Mahaut-Smith M, et al.
J Physiol . 2006 Nov; 578(Pt 1):85-97. PMID: 17110414
Ventricular arrhythmogenesis in long QT 3 syndrome (LQT3) involves both triggered activity and re-entrant excitation arising from delayed ventricular repolarization. Effects of specific L-type Ca2+ channel antagonism were explored in...
14.
Thomas G, Killeen M, Gurung I, Hakim P, Balasubramaniam R, Goddard C, et al.
J Physiol . 2006 Nov; 578(Pt 1):99-114. PMID: 17095567
Mutations within KCNE1 encoding a transmembrane protein which coassembles with K+ channels mediating slow K+, I(Ks), currents are implicated in cardiac action potential prolongation and ventricular arrhythmogenicity in long QT...