Matthew J Gaffrey
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Explore the profile of Matthew J Gaffrey including associated specialties, affiliations and a list of published articles.
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44
Citations
810
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Recent Articles
1.
Gluth A, Li X, Gritsenko M, Gaffrey M, Kim D, Lalli P, et al.
Mol Cell Proteomics
. 2024 Nov;
23(12):100881.
PMID: 39550035
Studying regulation of protein function at a systems level necessitates an understanding of the interplay among diverse posttranslational modifications (PTMs). A variety of proteomics sample processing workflows are currently used...
2.
De Jesus D, Zhang Z, Brown N, Li X, Xiao L, Hu J, et al.
Nat Cell Biol
. 2024 Feb;
26(3):421-437.
PMID: 38409327
Type 1 diabetes (T1D) is characterized by the destruction of pancreatic β-cells. Several observations have renewed the interest in β-cell RNA sensors and editors. Here, we report that -methyladenosine (mA)...
3.
Fu J, McKinley B, James B, Chrisler W, Markillie L, Gaffrey M, et al.
Plant J
. 2024 Feb;
118(5):1668-1688.
PMID: 38407828
Bioenergy sorghum is a low-input, drought-resilient, deep-rooting annual crop that has high biomass yield potential enabling the sustainable production of biofuels, biopower, and bioproducts. Bioenergy sorghum's 4-5 m stems account...
4.
Day N, Kelly S, Lui L, Mansfield T, Gaffrey M, Trejo J, et al.
Aging Cell
. 2024 Feb;
23(6):e14094.
PMID: 38332629
Oxidative stress is considered a contributor to declining muscle function and mobility during aging; however, the underlying molecular mechanisms remain poorly described. We hypothesized that greater levels of cysteine (Cys)...
5.
Abhange K, Kitata R, Zhang J, Wang Y, Gaffrey M, Liu T, et al.
J Proteome Res
. 2023 Dec;
23(1):386-396.
PMID: 38113368
Extracellular vesicle (EV) secretion has been observed in many types of both normal and tumor cells. EVs contain a variety of distinctive cargoes, allowing tumor-derived serum proteins in EVs to...
6.
Day N, Kelly S, Lui L, Mansfield T, Gaffrey M, Trejo J, et al.
medRxiv
. 2023 Nov;
PMID: 37986748
Oxidative stress is considered a contributor to declining muscle function and mobility during aging; however, the underlying molecular mechanisms remain poorly described. We hypothesized that greater levels of cysteine (Cys)...
7.
De Jesus D, Zhang Z, Brown N, Li X, Gaffrey M, Kahraman S, et al.
bioRxiv
. 2023 Feb;
PMID: 36824909
Type 1 Diabetes (T1D) is characterized by autoimmune-mediated destruction of insulin-producing β-cells. Several observations have renewed interest in the innate immune system as an initiator of the disease process against...
8.
Li X, Zhang T, Day N, Feng S, Gaffrey M, Qian W
Antioxidants (Basel)
. 2022 Nov;
11(11).
PMID: 36421458
Protein S-glutathionylation (SSG) is a reversible post-translational modification (PTM) featuring the conjugation of glutathione to a protein cysteine thiol. SSG can alter protein structure, activity, subcellular localization, and interaction with...
9.
Campbell M, Martin-Perez M, Egertson J, Gaffrey M, Wang L, Bammler T, et al.
Geroscience
. 2022 Nov;
44(6):2913-2924.
PMID: 36322234
The age-related decline in skeletal muscle mass and function is known as sarcopenia. Sarcopenia progresses based on complex processes involving protein dynamics, cell signaling, oxidative stress, and repair. We have...
10.
Day N, Zhang T, Gaffrey M, Zhao R, Fillmore T, Moore R, et al.
Free Radic Biol Med
. 2022 Oct;
193(Pt 1):373-384.
PMID: 36306991
Perturbation to the redox state accompanies many diseases and its effects are viewed through oxidation of biomolecules, including proteins, lipids, and nucleic acids. The thiol groups of protein cysteine residues...