Matthew J Gaffrey
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Explore the profile of Matthew J Gaffrey including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Anderson C, Zhang J, Markillie L, Mitchell H, Chrisler W, Gaffrey M, et al.
Appl Environ Microbiol
. 2022 Mar;
88(8):e0018822.
PMID: 35348388
Brown rot fungi dominate wood decomposition in coniferous forests, and their carbohydrate-selective mechanisms are of commercial interest. Brown rot was recently described as a two-step, sequential mechanism orchestrated by fungi...
12.
Zhang J, Markillie L, Mitchell H, Gaffrey M, Orr G, Schilling J
Fungal Genet Biol
. 2022 Feb;
159:103673.
PMID: 35150839
Brown rot fungi dominate the carbon degradation of northern terrestrial conifers. These fungi adapted unique genetic inventories to degrade lignocellulose and to rapidly release a large quantity of carbohydrates for...
13.
Whitson J, Martin-Perez M, Zhang T, Gaffrey M, Merrihew G, Huang E, et al.
Geroscience
. 2021 Sep;
43(5):2395-2412.
PMID: 34480713
It has been demonstrated that elamipretide (SS-31) rescues age-related functional deficits in the heart but the full set of mechanisms behind this have yet to be determined. We investigated the...
14.
Li X, Day N, Feng S, Gaffrey M, Lin T, Paurus V, et al.
Redox Biol
. 2021 Aug;
46:102111.
PMID: 34425387
Thiol-based post-translational modifications (PTMs) play a key role in redox-dependent regulation and signaling. Functional cysteine (Cys) sites serve as redox switches, regulated through multiple types of PTMs. Herein, we aim...
15.
Gaffrey M, Day N, Li X, Qian W
J Vis Exp
. 2021 Jul;
(172).
PMID: 34223836
Reversible oxidative modifications on protein thiols have recently emerged as important mediators of cellular function. Herein we describe the detailed procedure of a quantitative redox proteomics method that utilizes resin-assisted...
16.
Day N, Gaffrey M, Qian W
Antioxidants (Basel)
. 2021 Apr;
10(3).
PMID: 33807006
Post-translational modifications regulate the structure and function of proteins that can result in changes to the activity of different pathways. These include modifications altering the redox state of thiol groups...
17.
Xu Z, Pan C, Li X, Hao N, Zhang T, Gaffrey M, et al.
Biotechnol Biofuels
. 2021 Jan;
14(1):11.
PMID: 33413621
Background: Efficient utilization of all available carbons from lignocellulosic biomass is critical for economic efficiency of a bioconversion process to produce renewable bioproducts. However, the metabolic responses that enable Pseudomonas...
18.
Zhang T, Gaffrey M, Li X, Qian W
Am J Physiol Cell Physiol
. 2020 Dec;
320(2):C182-C194.
PMID: 33264075
The thiol redox proteome refers to all proteins whose cysteine thiols are subjected to various redox-dependent posttranslational modifications (PTMs) including glutathionylation (SSG), nitrosylation (SNO), sulfenylation (SOH), and sulfhydration (SSH). These...
19.
Wang J, Zhang T, Johnston C, Kim S, Gaffrey M, Chalupa D, et al.
Redox Biol
. 2020 Oct;
37:101758.
PMID: 33080441
E-cigarette (e-cig) aerosols are complex mixtures of various chemicals including humectants (propylene glycol (PG) and vegetable glycerin (VG)), nicotine, and various flavoring additives. Emerging research is beginning to challenge the...
20.
Duan J, Zhang T, Gaffrey M, Weitz K, Moore R, Li X, et al.
Redox Biol
. 2020 Aug;
36:101649.
PMID: 32750668
Posttranslational modifications of protein cysteine thiols play a significant role in redox regulation and the pathogenesis of human diseases. Herein, we report the characterization of the cellular redox landscape in...