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Matthew Ducar

Explore the profile of Matthew Ducar including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 1981
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Recent Articles
1.
Stover E, Oh C, Keskula P, Choudhury A, Tseng Y, Adalsteinsson V, et al.
Prostate . 2022 Jan; 82(5):584-597. PMID: 35084050
Background: Primary and metastatic prostate cancers have low mutation rates and recurrent alterations in a small set of genes, enabling targeted sequencing of prostate cancer-associated genes as an efficient approach...
2.
Kundra R, Zhang H, Sheridan R, Sirintrapun S, Wang A, Ochoa A, et al.
JCO Clin Cancer Inform . 2021 Feb; 5:221-230. PMID: 33625877
Purpose: Cancer classification is foundational for patient care and oncology research. Systems such as International Classification of Diseases for Oncology (ICD-O), Systematized Nomenclature of Medicine Clinical Terms (SNOMED-CT), and National...
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Burns M, Liao Z, Yamagata N, Pouliot G, Stevenson K, Neuberg D, et al.
Leukemia . 2018 Apr; 32(10):2126-2137. PMID: 29654263
The role of Hedgehog signaling in normal and malignant T-cell development is controversial. Recently, Hedgehog pathway mutations have been described in T-ALL, but whether mutational activation of Hedgehog signaling drives...
5.
Stachler M, Camarda N, Deitrick C, Kim A, Agoston A, Odze R, et al.
Gastroenterology . 2018 Apr; 155(1):156-167. PMID: 29608884
Background & Aims: Barrett's esophagus (BE) is the greatest risk factor for esophageal adenocarcinoma (EAC), but only a small proportion of patients with BE develop cancer. Biomarkers might be able...
6.
Melchardt T, Magnes T, Hufnagl C, Thorner A, Ducar M, Neureiter D, et al.
Eur J Cancer . 2018 Feb; 93:69-78. PMID: 29477794
Background: Tumour heterogeneity and clonal evolution within a cancer patient are deemed responsible for relapse in malignancies and present challenges to the principles of targeted therapy, for which treatment modality...
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Teot L, Schneider M, Thorner A, Tian J, Chi Y, Ducar M, et al.
Cancer . 2018 Feb; 124(9):1973-1981. PMID: 29461635
Background: Pediatric paired box 3:forkhead box protein O1 fusion-negative (PF-) rhabdomyosarcoma (RMS) represents a diverse spectrum of tumors with marked differences in histology, myogenic differentiation, and clinical behavior. Methods: This...
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Busch E, Hornick J, Umeton R, Albayrak A, Lindeman N, Macconaill L, et al.
Oncotarget . 2017 Nov; 8(49):85680-85691. PMID: 29156750
Metastases are involved in most cancer deaths. Evidence has suggested that cancer cell detachment from primary tumors might occur largely via the mechanism of epithelial-mesenchymal transition (EMT) activated by epigenetic...
9.
Qian Z, Rubinson D, Nowak J, Morales-Oyarvide V, Dunne R, Kozak M, et al.
JAMA Oncol . 2017 Nov; 4(3):e173420. PMID: 29098284
Importance: Although patients with resected pancreatic adenocarcinoma are at high risk for disease recurrence, few biomarkers are available to inform patient outcomes. Objective: To evaluate the alterations of the 4...
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Bi W, Greenwald N, Abedalthagafi M, Wala J, Gibson W, Agarwalla P, et al.
NPJ Genom Med . 2017 Jul; 2. PMID: 28713588
High-grade meningiomas frequently recur and are associated with high rates of morbidity and mortality. To determine the factors that promote the development and evolution of these tumors, we analyzed the...