Matthew D Lebar
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Explore the profile of Matthew D Lebar including associated specialties, affiliations and a list of published articles.
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36
Citations
752
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Recent Articles
21.
Majumdar R, Minocha R, Lebar M, Rajasekaran K, Long S, Carter-Wientjes C, et al.
Front Plant Sci
. 2019 Jun;
10:692.
PMID: 31178889
Polyamines (PAs) are ubiquitous polycations found in plants and other organisms that are essential for growth, development, and resistance against abiotic and biotic stresses. The role of PAs in plant...
22.
Gilbert M, Mack B, Moore G, Downey D, Lebar M, Joardar V, et al.
PLoS One
. 2018 Jul;
13(7):e0199169.
PMID: 29966003
Aspergillus flavus is a saprophytic fungus that infects corn, peanuts, tree nuts and other agriculturally important crops. Once the crop is infected the fungus has the potential to secrete one...
23.
Lebar M, Cary J, Majumdar R, Carter-Wientjes C, Mack B, Wei Q, et al.
Fungal Genet Biol
. 2018 Apr;
116:14-23.
PMID: 29674152
Aspergillus flavus can colonize important food staples and produce aflatoxins, a group of toxic and carcinogenic secondary metabolites. Previous in silico analysis of the A. flavus genome revealed 56 gene...
24.
Gilbert M, Majumdar R, Rajasekaran K, Chen Z, Wei Q, Sickler C, et al.
Planta
. 2018 Mar;
247(6):1465-1473.
PMID: 29541880
Expressing an RNAi construct in maize kernels that targets the gene for alpha-amylase in Aspergillus flavus resulted in suppression of alpha-amylase (amy1) gene expression and decreased fungal growth during in...
25.
Gilbert M, Medina A, Mack B, Lebar M, Rodriguez A, Bhatnagar D, et al.
Toxins (Basel)
. 2017 Dec;
10(1).
PMID: 29271897
is a saprophytic fungus that may colonize several important crops, including cotton, maize, peanuts and tree nuts. Concomitant with colonization is its potential to secrete mycotoxins, of which the most...
26.
Moison E, Xie R, Zhang G, Lebar M, Meredith T, Kahne D
ACS Chem Biol
. 2017 Mar;
12(4):928-932.
PMID: 28248483
Lipopolysaccharide (LPS) biogenesis in Gram-negative organisms involves its biosynthesis in the cytoplasm and subsequent transport across three cellular compartments to the cell surface. We developed a fluorescent probe that allows...
27.
Grabowicz M, Andres D, Lebar M, Malojcic G, Kahne D, Silhavy T
Elife
. 2015 Jan;
3:e05334.
PMID: 25551294
The lipopolysaccharide (LPS) forms the surface-exposed leaflet of the outer membrane (OM) of Gram-negative bacteria, an organelle that shields the underlying peptidoglycan (PG) cell wall. Both LPS and PG are...
28.
Waterman C, Calcul L, Beau J, Ma W, Lebar M, von Salm J, et al.
Med Res Rev
. 2014 Dec;
36(1):144-68.
PMID: 25545963
The ongoing search for effective antiplasmodial agents remains essential in the fight against malaria worldwide. Emerging parasitic drug resistance places an urgent need to explore chemotherapies with novel structures and...
29.
Qiao Y, Lebar M, Schirner K, Schaefer K, Tsukamoto H, Kahne D, et al.
J Am Chem Soc
. 2014 Oct;
136(42):14678-81.
PMID: 25291014
Penicillin-binding proteins (PBPs) are involved in the synthesis and remodeling of bacterial peptidoglycan (PG). Staphylococcus aureus expresses four PBPs. Genetic studies in S. aureus have implicated PBP4 in the formation...
30.
Lebar M, May J, Meeske A, Leiman S, Lupoli T, Tsukamoto H, et al.
J Am Chem Soc
. 2014 Jul;
136(31):10874-7.
PMID: 25036369
The peptidoglycan precursor, Lipid II, produced in the model Gram-positive bacterium Bacillus subtilis differs from Lipid II found in Gram-negative bacteria such as Escherichia coli by a single amidation on...