Matthew C Sinton
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Explore the profile of Matthew C Sinton including associated specialties, affiliations and a list of published articles.
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15
Citations
167
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Recent Articles
1.
Sinton M, Shorthouse O, Costain A, Quintana J
Immunity
. 2025 Jan;
58(1):15-17.
PMID: 39813991
Interleukin-17 plays a major role in controlling adipose tissue homeostasis. In a recent study published in Nature, Douglas et al. demonstrate that time-of-day-dependent expression of interleukin-17 by tissue-resident innate lymphocytes...
2.
Lay A, Tran V, Nair V, Betin V, Hurcombe J, Barrington A, et al.
Nat Commun
. 2024 Nov;
15(1):10018.
PMID: 39562547
Diabetic kidney disease (DKD) is the leading cause of end stage kidney failure worldwide, of which cellular insulin resistance is a major driver. Here, we study key human kidney cell...
3.
Sinton M, Kajimura S
FEBS J
. 2024 Oct;
PMID: 39428707
Adipose tissue is a rich source of diverse cell populations, including immune cells, adipocytes and stromal cells. Interactions between these different cell types are now appreciated to be critical for...
4.
Sinton M, Chandrasegaran P, Capewell P, Cooper A, Girard A, Ogunsola J, et al.
Nat Commun
. 2024 Feb;
15(1):1833.
PMID: 38418827
No abstract available.
5.
Quintana J, Sinton M, Chandrasegaran P, Dubey L, Ogunsola J, Al Samman M, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002389.
PMID: 37983289
The meningeal space is a critical brain structure providing immunosurveillance for the central nervous system (CNS), but the impact of infections on the meningeal immune landscape is far from being...
6.
Sinton M, Chandrasegaran P, Capewell P, Cooper A, Girard A, Ogunsola J, et al.
Nat Commun
. 2023 Nov;
14(1):7070.
PMID: 37923768
In the skin, Trypanosoma brucei colonises the subcutaneous white adipose tissue, and is proposed to be competent for forward transmission. The interaction between parasites, adipose tissue, and the local immune...
7.
Quintana J, Sinton M, Chandrasegaran P, Lestari A, Heslop R, Cheaib B, et al.
Nat Commun
. 2023 Aug;
14(1):5279.
PMID: 37644007
African trypanosomes colonise the skin to ensure parasite transmission. However, how the skin responds to trypanosome infection remains unresolved. Here, we investigate the local immune response of the skin in...
8.
Chandrasegaran P, Lestari A, Sinton M, Gopalakrishnan J, Quintana J
F1000Res
. 2023 Aug;
12:437.
PMID: 37588058
Sleeping sickness is caused by the extracellular parasite and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder. Sleeping...
9.
Quintana J, Chandrasegaran P, Sinton M, Briggs E, Otto T, Heslop R, et al.
Nat Commun
. 2022 Sep;
13(1):5752.
PMID: 36180478
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and induces profound reactivity of glial cells and neuroinflammation when the parasites colonise the central nervous...
10.
Sinton M
Immunol Cell Biol
. 2022 Jul;
100(10):757-758.
PMID: 35849026
This commentary focuses on the necessity for LGBTQ+ people working in academia to feel safe, without fear of repercussions for revealing or expressing their identity. I discuss the importance of...