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Matthew B Dowling

Explore the profile of Matthew B Dowling including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 124
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Recent Articles
1.
Choudhary H, Rudy M, Dowling M, Raghavan S
ACS Appl Mater Interfaces . 2021 Mar; 13(12):13958-13967. PMID: 33749251
Bleeding from injuries to the torso region is a leading cause of fatalities in the military and in young adults. Such bleeding cannot be stopped by applying direct pressure (compression)...
2.
Dowling M, MacIntire I, White J, Narayan M, Duggan M, King D, et al.
ACS Biomater Sci Eng . 2021 Jan; 1(6):440-447. PMID: 33445247
Hemorrhage (severe blood loss) from traumatic injury is a leading cause of death for soldiers in combat and for young civilians. In some cases, hemorrhage can be stopped by applying...
3.
MacIntire I, Dowling M, Raghavan S
Langmuir . 2020 Jul; 36(29):8357-8366. PMID: 32678610
Amphiphilic biopolymers such as hydrophobically modified chitosan (hmC) have been shown to convert liquid blood into elastic gels. This interesting property could make hmC useful as a hemostatic agent in...
4.
Javvaji V, Dowling M, Oh H, White I, Raghavan S
Biomater Sci . 2020 Jun; 2(7):1016-1023. PMID: 32481975
Polymer hydrogels have long been used to hold and culture biological cells within their three-dimensional (3-D) matrices. Typically, in such cases, the cells are passively entrapped in a mesh of...
5.
Logun M, Dowling M, Raghavan S, Wallace M, Schmiedt C, Stice S, et al.
J Surg Res . 2019 Mar; 239:269-277. PMID: 30884383
Background: A novel injectable expanding foam based on hydrophobically modified chitosan (HM-CS) was developed to improve hemostasis during surgeries. HM-CS is an amphiphilic derivative of the natural biopolymer chitosan (CS);...
6.
Chaturvedi A, Dowling M, Gustin J, Scalea T, Raghavan S, Pasley J, et al.
J Surg Res . 2016 Dec; 207:45-52. PMID: 27979487
Background: Currently, the standard of care for treating severe hemorrhage in a military setting is Combat Gauze (CG). Previous work has shown that hydrophobically modified chitosan (hm-C) has significant hemostatic...
7.
Dowling M, Chaturvedi A, MacIntire I, Javvaji V, Gustin J, Raghavan S, et al.
Injury . 2016 Jul; 47(10):2105-2109. PMID: 27423307
Introduction: Alginate is a biocompatible polysaccharide that is commonly used in the pharmaceutical, biomedical, cosmetic, and food industries. Though solid dressings composed of alginate can absorb water and promote wound...
8.
Dowling M, Smith W, Balogh P, Duggan M, MacIntire I, Harris E, et al.
J Surg Res . 2014 Jul; 193(1):316-23. PMID: 25016441
Background: Trauma represents a significant public health burden, and hemorrhage alone is responsible for 40% of deaths within the first 24 h after injury. Noncompressible hemorrhage accounts for the majority...
9.
Dowling M, Bagal A, Raghavan S
Langmuir . 2013 Aug; 29(25):7993-8. PMID: 23984817
We describe a new class of hierarchical containers that are formed via single-step assembly and, at a later time, self-destruct because of their packaged contents. These containers are spherical capsules...
10.
Gupta A, Terrell J, Fernandes R, Dowling M, Payne G, Raghavan S, et al.
Biotechnol Bioeng . 2012 Aug; 110(2):552-62. PMID: 22903626
We demonstrate that "nanofactory"-loaded biopolymer capsules placed in the midst of a bacterial population can direct bacterial communication. Quorum sensing (QS) is a process by which bacteria communicate through small-molecules,...