Matteo Sorge
Overview
Explore the profile of Matteo Sorge including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
245
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0
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Recent Articles
1.
Acquarone D, Bertero A, Brancaccio M, Sorge M
J Cachexia Sarcopenia Muscle
. 2024 Dec;
16(1):e13659.
PMID: 39707668
Despite significant progress in understanding the molecular aetiology of muscle atrophy, there is still a great need for new targets and drugs capable of counteracting muscle wasting. The role of...
2.
Sorge M, Savore G, Gallo A, Acquarone D, Sbroggio M, Velasco S, et al.
EMBO Mol Med
. 2024 Sep;
16(10):2450-2484.
PMID: 39271959
Defining the molecular mechanisms underlying cardiac resilience is crucial to find effective approaches to protect the heart. A physiologic level of ROS is produced in the heart by fatty acid...
3.
Arina P, Sorge M, Gallo A, Di Mauro V, Vitale N, Cappello P, et al.
Shock
. 2022 Mar;
57(6):318-325.
PMID: 35271535
Aim: Sepsis-induced cardiomyopathy is commonplace and carries an increased risk of death. Melusin, a cardiac muscle-specific chaperone, exerts cardioprotective function under varied stressful conditions through activation of the AKT pathway....
4.
Penna C, Sorge M, Tullio F, Comita S, Femmino S, Brancaccio M, et al.
Biology (Basel)
. 2022 Jan;
11(1).
PMID: 35053144
Background: Treatment of myocardial ischemia/reperfusion (IR) injury is still an unmet clinical need. A large variability of remote ischemic conditioning (RIC) protection has been reported; however, no studies have considered...
5.
Poggio P, Sorge M, Secli L, Brancaccio M
Front Cell Dev Biol
. 2021 Nov;
9:735529.
PMID: 34722515
HSP90 is released by cancer cells in the tumor microenvironment where it associates with different co-chaperones generating complexes with specific functions, ranging from folding and activation of extracellular clients to...
6.
Gorza L, Sorge M, Secli L, Brancaccio M
Cells
. 2021 Jan;
10(1).
PMID: 33401549
The loss of muscle mass and force characterizes muscle atrophy in several different conditions, which share the expression of atrogenes and the activation of their transcriptional regulators. However, attempts to...
7.
Secli L, Sorge M, Morotti A, Brancaccio M
Front Bioeng Biotechnol
. 2020 Jun;
8:411.
PMID: 32528937
Chronic or acute insults to the myocardium are responsible for the onset of cardiomyopathy and heart failure. Due to the poor regenerative ability of the human adult heart, the survival...
8.
Vitadello M, Sorge M, Percivalle E, Germinario E, Danieli-Betto D, Turco E, et al.
J Cachexia Sarcopenia Muscle
. 2020 Mar;
11(3):802-819.
PMID: 32154658
Background: Unloading/disuse induces skeletal muscle atrophy in bedridden patients and aged people, who cannot prevent it by means of exercise. Because interventions against known atrophy initiators, such as oxidative stress...
9.
Gazzano E, Buondonno I, Marengo A, Rolando B, Chegaev K, Kopecka J, et al.
Cancer Lett
. 2019 May;
456:29-39.
PMID: 31047947
Doxorubicin (dox) is one of the first-line drug in osteosarcoma treatment but its effectiveness is limited by the efflux pump P-glycoprotein (Pgp) and by the onset of cardiotoxicity. We previously...
10.
Cavallari E, Carrera C, Sorge M, Bonne G, Muchir A, Aime S, et al.
Sci Rep
. 2018 Jun;
8(1):8366.
PMID: 29849091
Many imaging methods have been proposed to act as surrogate markers of organ damage, yet for many candidates the essential biomarkers characteristics of the injured organ have not yet been...