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Matteo Simonelli

Explore the profile of Matteo Simonelli including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 1164
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Recent Articles
1.
Bono B, Grimi A, Di Toro A, Ninatti G, Franzini A, Rossini Z, et al.
Neurosurgery . 2025 Jan; PMID: 39878484
Background And Objectives: Understanding and managing seizure activity is crucial in neuro-oncology, especially for highly epileptogenic lesions like isocitrate dehydrogenase (IDH)-mutant gliomas. Advanced MRI techniques such as diffusion tensor imaging...
2.
Cella E, Bosio A, Persico P, Caccese M, Padovan M, Losurdo A, et al.
Cancer Treat Rev . 2024 Dec; 132:102866. PMID: 39709267
No abstract available.
3.
Cella E, Bosio A, Persico P, Caccese M, Padovan M, Losurdo A, et al.
Cancer Treat Rev . 2024 Nov; 131:102850. PMID: 39531943
Gliomas are the most common primary malignant brain tumours in adults. Despite decades of research into novel therapeutic approaches, the prognosis remains poor. PARP1-2 are critical for DNA repair, cell...
4.
Scirgolea C, Sottile R, De Luca M, Susana A, Carnevale S, Puccio S, et al.
Nat Immunol . 2024 Aug; 25(10):1845-1857. PMID: 39198631
CD8 T cells control tumors but inevitably become dysfunctional in the tumor microenvironment. Here, we show that sodium chloride (NaCl) counteracts T cell dysfunction to promote cancer regression. NaCl supplementation...
5.
Tropeano M, Raspagliesi L, Bono B, Baram A, Rossini Z, Franzini A, et al.
Acta Neurochir (Wien) . 2024 Apr; 166(1):196. PMID: 38676720
Background: The prognostic value of the extent of resection in the management of Glioblastoma is a long-debated topic, recently widened by the 2022 RANO-Resect Classification, which advocates for the resection...
6.
Di Nunno V, Lombardi G, Simonelli M, Minniti G, Mastronuzzi A, Di Ruscio V, et al.
J Neurooncol . 2024 Mar; 167(1):145-154. PMID: 38457090
Purpose: Adult Diffuse midline glioma (DMG) is a very rare disease. DMGs are currently treated with radiotherapy and chemotherapy even if only a few retrospective studies assessed the impact on...
7.
Miele E, Anghileri E, Calatozzolo C, Lazzarini E, Patrizi S, Ciolfi A, et al.
Cancer Lett . 2024 Feb; 588:216711. PMID: 38423245
Five-year glioblastoma (GBM) survivors (LTS) are the minority of the isocitrate dehydrogenase (IDH)-wild-type GBM patients, and their molecular fingerprint is still largely unexplored. This multicenter retrospective study analyzed a large...
8.
Robbrecht D, Grob J, Bechter O, Simonelli M, Doger B, Borbath I, et al.
Clin Transl Sci . 2024 Feb; 17(2):e13736. PMID: 38362837
SAR439459, a 'second-generation' human anti-transforming growth factor-beta (TGFβ) monoclonal antibody, inhibits all TGFβ isoforms and improves the antitumor activity of anti-programmed cell death protein-1 therapeutics. This study reports the pharmacodynamics...
9.
Losurdo A, Di Muzio A, Cianciotti B, Dipasquale A, Persico P, Barigazzi C, et al.
Cancers (Basel) . 2024 Feb; 16(3). PMID: 38339353
Glioblastoma (GBM) is the most aggressive and lethal primary brain tumor, bearing a survival estimate below 10% at five years, despite standard chemoradiation treatment. At recurrence, systemic treatment options are...
10.
Dipasquale A, Franceschi E, Lombardi G, Simonelli M
Neurooncol Adv . 2024 Feb; 6(1):vdae003. PMID: 38312228
No abstract available.