Matteo Perino
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Explore the profile of Matteo Perino including associated specialties, affiliations and a list of published articles.
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6
Citations
231
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Recent Articles
1.
Loh C, van Genesen S, Perino M, Bark M, Veenstra G
Nat Commun
. 2021 Dec;
12(1):6985.
PMID: 34848733
Polycomb Repressive Complex 2 (PRC2) is crucial for the coordinated expression of genes during early embryonic development, catalyzing histone H3 lysine 27 trimethylation. Two distinct PRC2 complexes, PRC2.1 and PRC2.2,...
2.
Perino M, van Mierlo G, Loh C, Wardle S, Zijlmans D, Marks H, et al.
Stem Cell Reports
. 2020 Aug;
15(6):1287-1300.
PMID: 32763159
Polycomb Repressive Complex 2 (PRC2) plays an essential role in gene repression during development, catalyzing H3 lysine 27 trimethylation (H3K27me3). MTF2 in the PRC2.1 sub-complex, and JARID2 in PRC2.2, are...
3.
Lindeboom R, Smits A, Perino M, Veenstra G, Vermeulen M
Cold Spring Harb Protoc
. 2018 Aug;
2019(6).
PMID: 30104410
Early development is characterized by a poor correlation between global mRNA and protein abundances due to maternal mRNA and protein loading. Therefore, proteome profiling is necessary to study gene expression...
4.
Perino M, van Mierlo G, Karemaker I, van Genesen S, Vermeulen M, Marks H, et al.
Nat Genet
. 2018 May;
50(7):1002-1010.
PMID: 29808031
Polycomb-mediated repression of gene expression is essential for development, with a pivotal role played by trimethylation of histone H3 lysine 27 (H3K27me3), which is deposited by Polycomb Repressive Complex 2...
5.
Perino M, Veenstra G
Dev Cell
. 2016 Sep;
38(6):610-20.
PMID: 27676434
Chromatin structure is intimately connected with gene expression and cell identity. Here we review recent advances in the field and discuss how establishment of cell identity during development is accompanied...
6.
Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs
Smits A, Lindeboom R, Perino M, van Heeringen S, Veenstra G, Vermeulen M
Nucleic Acids Res
. 2014 Jul;
42(15):9880-91.
PMID: 25056316
While recent developments in genomic sequencing technology have enabled comprehensive transcriptome analyses of single cells, single cell proteomics has thus far been restricted to targeted studies. Here, we perform global...