Matt Thomson
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Explore the profile of Matt Thomson including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
638
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Recent Articles
1.
Yang F, Liu S, Lee H, Phillips R, Thomson M
Nat Mater
. 2025 Jan;
PMID: 39880931
Cells use 'active' energy-consuming motor and filament protein networks to control micrometre-scale transport and fluid flows. Biological active materials could be used in dynamically programmable devices that achieve spatial and...
2.
Lourenco A, Subramanian A, Spencer R, Anaya M, Miao J, Fu W, et al.
bioRxiv
. 2025 Jan;
PMID: 39803556
Proteins have proven to be useful agents in a variety of fields, from serving as potent therapeutics to enabling complex catalysis for chemical manufacture. However, they remain difficult to design...
3.
Santorelli M, Bhamidipati P, Courte J, Swedlund B, Jain N, Poon K, et al.
Nat Commun
. 2024 Nov;
15(1):9867.
PMID: 39562554
A major goal in synthetic development is to build gene regulatory circuits that control patterning. In natural development, an interplay between mechanical and chemical communication shapes the dynamics of multicellular...
4.
Hirokawa S, Lee H, Banks R, Duarte A, Najma B, Thomson M, et al.
ArXiv
. 2024 Sep;
PMID: 39253630
Motor-driven cytoskeletal remodeling in cellular systems can often be accompanied by a diffusive-like effect at local scales, but distinguishing the contributions of the ordering process, such as active contraction of...
5.
Polonsky M, Gerhardt L, Yun J, Koppitch K, Colon K, Amrhein H, et al.
Nat Commun
. 2024 Sep;
15(1):7010.
PMID: 39237549
Kidney injury disrupts the intricate renal architecture and triggers limited regeneration, together with injury-invoked inflammation and fibrosis. Deciphering the molecular pathways and cellular interactions driving these processes is challenging due...
6.
Garibyan M, Hoffman T, Makaske T, Do S, Wu Y, Williams B, et al.
Nat Commun
. 2024 Aug;
15(1):6490.
PMID: 39090120
No abstract available.
7.
Garibyan M, Hoffman T, Makaske T, Do S, Wu Y, Williams B, et al.
Nat Commun
. 2024 Jul;
15(1):5891.
PMID: 39003263
Synthetic Notch (synNotch) receptors are genetically encoded, modular synthetic receptors that enable mammalian cells to detect environmental signals and respond by activating user-prescribed transcriptional programs. Although some materials have been...
8.
Huycke T, Hakkinen T, Miyazaki H, Srivastava V, Barruet E, McGinnis C, et al.
Cell
. 2024 May;
187(12):3072-3089.e20.
PMID: 38781967
Tissue folds are structural motifs critical to organ function. In the intestine, bending of a flat epithelium into a periodic pattern of folds gives rise to villi, finger-like protrusions that...
9.
Subramanian A, Martinez Z, Lourenco A, Liu S, Thomson M
bioRxiv
. 2024 Jan;
PMID: 38187750
The combinatorial scale of amino-acid sequence-space has traditionally precluded substantive study of the full protein sequence-structure map. It remains unknown, for instance, how much of the vast uncharted landscape of...
10.
Chen X, Chen S, Thomson M
Nat Comput Sci
. 2024 Jan;
2(6):387-398.
PMID: 38177588
Sequencing costs currently prohibit the application of single-cell mRNA-seq to many biological and clinical analyses. Targeted single-cell mRNA-sequencing reduces sequencing costs by profiling reduced gene sets that capture biological information...