Matilde Merlin
Overview
Explore the profile of Matilde Merlin including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
144
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Recent Articles
1.
Rigillo G, Pressi G, Bertaiola O, Guarnerio C, Merlin M, Zambonin R, et al.
Pharmaceutics
. 2025 Jan;
17(1).
PMID: 39861784
(L.) DC., commonly known as Japanese pepper, is a deciduous shrub native to East Asia. Its berries are widely used as a spice, known for imparting a distinctive, tingly numbing...
2.
Pressi G, Rigillo G, Governa P, Borgonetti V, Baini G, Rizzi R, et al.
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678869
In the last years, the medicinal plant (L.) Britton has gained scientific interest because leaf extracts, due to the presence of rosmarinic acid and other polyphenols, have shown anti-allergic and...
3.
Zampieri R, Brozzetti A, Pericolini E, Bartoloni E, Gabrielli E, Roselletti E, et al.
Sci Adv
. 2020 Jun;
6(19):eaaz0295.
PMID: 32494704
Plant viruses are natural, self-assembling nanostructures with versatile and genetically programmable shells, making them useful in diverse applications ranging from the development of new materials to diagnostics and therapeutics. Here,...
4.
Bertini E, Merlin M, Gecchele E, Puggia A, Brozzetti A, Commisso M, et al.
Front Plant Sci
. 2018 May;
9:572.
PMID: 29765386
Type-1 diabetes (T1D) is a metabolic disease involving the autoimmune destruction of insulin-producing pancreatic beta cells. It is often diagnosed by the detection of autoantibodies, typically those recognizing insulin itself...
5.
Merlin M, Pezzotti M, Avesani L
Br J Clin Pharmacol
. 2016 Apr;
83(1):71-81.
PMID: 27037892
Molecular farming is the use of plants for the production of high value recombinant proteins. Over the last 25 years, molecular farming has achieved the inexpensive, scalable and safe production...
6.
Merlin M, Gecchele E, Arcalis E, Remelli S, Brozzetti A, Pezzotti M, et al.
Biotechnol J
. 2015 Dec;
11(4):542-53.
PMID: 26710327
Plants have emerged as competitive production platforms for pharmaceutical proteins that are required in large quantities. One example is the 65-kDa isoform of human glutamic acid decarboxylase (GAD65), a major...
7.
Tinazzi E, Merlin M, Bason C, Beri R, Zampieri R, Lico C, et al.
Front Plant Sci
. 2015 Dec;
6:1080.
PMID: 26648961
Plants are ideal for the production of protein-based nanomaterials because they synthesize and assemble complex multimeric proteins that cannot be expressed efficiently using other platforms. Plant viruses can be thought...
8.
Pinnola A, Ghin L, Gecchele E, Merlin M, Alboresi A, Avesani L, et al.
J Biol Chem
. 2015 Aug;
290(40):24340-54.
PMID: 26260788
Oxygenic photosynthetic organisms evolved mechanisms for thermal dissipation of energy absorbed in excess to prevent formation of reactive oxygen species. The major and fastest component, called non-photochemical quenching, occurs within...
9.
Gecchele E, Merlin M, Brozzetti A, Falorni A, Pezzotti M, Avesani L
J Vis Exp
. 2015 Apr;
(97).
PMID: 25867956
Plant-based systems are considered a valuable platform for the production of recombinant proteins as a result of their well-documented potential for the flexible, low-cost production of high-quality, bioactive products. In...
10.
Gecchele E, Schillberg S, Merlin M, Pezzotti M, Avesani L
J Chromatogr B Analyt Technol Biomed Life Sci
. 2014 May;
960:34-42.
PMID: 24786219
The 65-kDa isoform of human glutamic acid decarboxylase (hGAD65) is a major autoantigen in autoimmune diabetes. The heterologous production of hGAD65 for diagnostic and therapeutic applications is hampered by low...