Mathieu Parisien
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Explore the profile of Mathieu Parisien including associated specialties, affiliations and a list of published articles.
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5
Citations
186
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Recent Articles
1.
Fader L, Brault M, Desjardins J, Dansereau N, Lamorte L, Tremblay S, et al.
ACS Med Chem Lett
. 2016 May;
7(5):525-30.
PMID: 27190604
A high-throughput screen based on a viral replication assay was used to identify inhibitors of the human cytomegalovirus. Using this approach, hit compound 1 was identified as a 4 μM...
2.
Fader L, Malenfant E, Parisien M, Carson R, Bilodeau F, Landry S, et al.
ACS Med Chem Lett
. 2014 Jun;
5(4):422-7.
PMID: 24900852
An assay recapitulating the 3' processing activity of HIV-1 integrase (IN) was used to screen the Boehringer Ingelheim compound collection. Hit-to-lead and lead optimization beginning with compound 1 established the...
3.
Campeau L, Parisien M, Jean A, Fagnou K
J Am Chem Soc
. 2006 Jan;
128(2):581-90.
PMID: 16402846
A catalyst for the intramolecular direct arylation of a broad range of simple and heterocyclic arenes with aryl iodides, bromides, and chlorides has been developed. These reactions occur in excellent...
4.
Parisien M, Valette D, Fagnou K
J Org Chem
. 2005 Sep;
70(19):7578-84.
PMID: 16149786
[reactions: see text] Palladium hydroxide on carbon (Pearlman's catalyst) effectively catalyzes direct arylation reactions of aryl iodides and bromides, providing excellent arylation-to-hydrodehalogenation ratios (>30:1) with broad scope for both intra-...
5.
Campeau L, Parisien M, Leblanc M, Fagnou K
J Am Chem Soc
. 2004 Jul;
126(30):9186-7.
PMID: 15281800
In this Communication, we describe direct arylation reactions with improved scope and catalyst activity for the intramolecular formation of biaryl compounds. This was achieved through the establishment of a highly...