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Mathieu Mequinion

Explore the profile of Mathieu Mequinion including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 228
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Recent Articles
1.
Reed F, Reichenbach A, Dempsey H, Clarke R, Mequinion M, Stark R, et al.
Mol Metab . 2023 Sep; 77:101803. PMID: 37690518
Objective: An environmental context, which reliably predicts food availability, can increase the appetitive food drive within the same environment context. However, hunger is required for the development of such a...
2.
Clarke R, Voigt K, Reichenbach A, Stark R, Bharania U, Dempsey H, et al.
Biol Psychiatry . 2022 Nov; 93(4):309-321. PMID: 36400605
Background: A greater understanding of how the brain controls appetite is fundamental to developing new approaches for treating diseases characterized by dysfunctional feeding behavior, such as obesity and anorexia nervosa....
3.
Reichenbach A, Clarke R, Stark R, Lockie S, Mequinion M, Dempsey H, et al.
Elife . 2022 Jan; 11. PMID: 35018884
Agouti-related peptide (AgRP) neurons increase motivation for food, however, whether metabolic sensing of homeostatic state in AgRP neurons potentiates motivation by interacting with dopamine reward systems is unexplored. As a...
4.
Dodd G, Kim S, Mequinion M, Xirouchaki C, Bruning J, Andrews Z, et al.
Sci Adv . 2021 Feb; 7(9). PMID: 33637536
The importance of hypothalamic insulin signaling on feeding and glucose metabolism remains unclear. We report that insulin acts on AgRP neurons to acutely decrease meal size and thereby limit postprandial...
5.
Hornsby A, Buntwal L, Carisi M, Santos V, Johnston F, Roberts L, et al.
Cell Rep Med . 2020 Oct; 1(7):100120. PMID: 33103129
Blood-borne factors regulate adult hippocampal neurogenesis and cognition in mammals. We report that elevating circulating unacylated-ghrelin (UAG), using both pharmacological and genetic methods, reduced hippocampal neurogenesis and plasticity in mice....
6.
Mequinion M, Foldi C, Andrews Z
Front Nutr . 2020 Jan; 6:190. PMID: 31998738
Anorexia Nervosa (AN) is viewed as primarily a psychiatric disorder owing to the considerable behavioral and genetic overlap with mood disorders and other psychiatric traits. However, the recent reconceptualization of...
7.
Cuvelier E, Mequinion M, Leghay C, Sibran W, Stievenard A, Sarchione A, et al.
Front Mol Neurosci . 2018 Oct; 11:321. PMID: 30333721
Parkinson's disease is a progressive neurodegenerative disorder characterized by loss of dopaminergic neurons, pathological accumulation of alpha-synuclein and motor symptoms, but also by non-motor symptoms. Metabolic abnormalities including body weight...
8.
Lockie S, Stark R, Mequinion M, Chng S, Kong D, Spanswick D, et al.
Endocrinology . 2018 Sep; 159(11):3605-3614. PMID: 30204871
Metabolic feedback from the periphery to the brain results from a dynamic physiologic fluctuation of nutrients and hormones, including glucose and fatty acids, ghrelin, leptin, and insulin. The specific interactions...
9.
Reichenbach A, Stark R, Mequinion M, Lockie S, Lemus M, Mynatt R, et al.
FASEB J . 2018 Jun; :fj201800634R. PMID: 29932868
Hunger-sensing agouti-related peptide (AgRP) neurons ensure survival by adapting metabolism and behavior to low caloric environments. This adaption is accomplished by consolidating food intake, suppressing energy expenditure, and maximizing fat...
10.
Reichenbach A, Mequinion M, Bayliss J, Lockie S, Lemus M, Mynatt R, et al.
Endocrinology . 2018 Apr; 159(6):2473-2483. PMID: 29697769
Behavioral adaptation to periods of varying food availability is crucial for survival, and agouti-related protein (AgRP) neurons have been associated with entrainment to temporal restricted feeding. We have shown that...