Mathias Munschauer
Overview
Explore the profile of Mathias Munschauer including associated specialties, affiliations and a list of published articles.
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28
Citations
8508
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Recent Articles
1.
Aydin J, Gabel A, Zielinski S, Ganskih S, Schmidt N, Hartigan C, et al.
Nucleic Acids Res
. 2024 Jan;
52(5):e26.
PMID: 38281241
RNA-protein interactions determine the cellular fate of RNA and are central to regulating gene expression outcomes in health and disease. To date, no method exists that is able to identify...
2.
Trifault B, Mamontova V, Cossa G, Ganskih S, Wei Y, Hofstetter J, et al.
Nucleic Acids Res
. 2024 Jan;
52(6):3050-3068.
PMID: 38224452
RNA-binding proteins emerge as effectors of the DNA damage response (DDR). The multifunctional non-POU domain-containing octamer-binding protein NONO/p54nrb marks nuclear paraspeckles in unperturbed cells, but also undergoes re-localization to the...
3.
Schmidt N, Ganskih S, Wei Y, Gabel A, Zielinski S, Keshishian H, et al.
Cell
. 2023 Oct;
186(22):4834-4850.e23.
PMID: 37794589
Regulation of viral RNA biogenesis is fundamental to productive SARS-CoV-2 infection. To characterize host RNA-binding proteins (RBPs) involved in this process, we biochemically identified proteins bound to genomic and subgenomic...
4.
Pekayvaz K, Leunig A, Kaiser R, Joppich M, Brambs S, Janjic A, et al.
Nat Commun
. 2022 Feb;
13(1):1018.
PMID: 35197461
The antiviral immune response to SARS-CoV-2 infection can limit viral spread and prevent development of pneumonic COVID-19. However, the protective immunological response associated with successful viral containment in the upper...
5.
Ludwig L, Lareau C, Bao E, Liu N, Utsugisawa T, Tseng A, et al.
Blood
. 2022 Jan;
139(16):2534-2546.
PMID: 35030251
Master regulators, such as the hematopoietic transcription factor (TF) GATA1, play an essential role in orchestrating lineage commitment and differentiation. However, the precise mechanisms by which such TFs regulate transcription...
6.
Schmidt N, Munschauer M
Biospektrum (Heidelb)
. 2021 Jul;
27(4):376-379.
PMID: 34219983
Using RNA antisense purification and mass spectrometry, we identified more than 100 human proteins that directly and specifically bind SARS-CoV-2 RNA in infected cells. To gain insights into the functions...
7.
Gonzalez-Perez A, Stempel M, Wyler E, Urban C, Piras A, Hennig T, et al.
mBio
. 2021 May;
12(3).
PMID: 33947766
Interferon-stimulated gene products (ISGs) play a crucial role in early infection control. The ISG zinc finger CCCH-type antiviral protein 1 (ZAP/ZC3HAV1) antagonizes several RNA viruses by binding to CG-rich RNA...
8.
Schmidt N, Lareau C, Keshishian H, Ganskih S, Schneider C, Hennig T, et al.
Nat Microbiol
. 2020 Dec;
6(3):339-353.
PMID: 33349665
Characterizing the interactions that SARS-CoV-2 viral RNAs make with host cell proteins during infection can improve our understanding of viral RNA functions and the host innate immune response. Using RNA...
9.
Gandhi M, Gross M, Holler J, Coggins S, Patil N, Leupold J, et al.
Nat Commun
. 2020 Jun;
11(1):3214.
PMID: 32587247
Long intergenic non-coding RNA-Nucleotide Metabolism Regulator (lincNMR) is a long non-coding RNA (lncRNA) which is induced in hepatocellular carcinoma. Its depletion invokes a proliferation defect, triggers senescence and inhibits colony...
10.
Basak A, Munschauer M, Lareau C, Montbleau K, Ulirsch J, Hartigan C, et al.
Nat Genet
. 2020 Jan;
52(2):138-145.
PMID: 31959994
Increased production of fetal hemoglobin (HbF) can ameliorate the severity of sickle cell disease and β-thalassemia. BCL11A represses the genes encoding HbF and regulates human hemoglobin switching through variation in...