Mathangi Gopalakrishnan
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Explore the profile of Mathangi Gopalakrishnan including associated specialties, affiliations and a list of published articles.
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66
Citations
243
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Recent Articles
1.
Nyman K, Decker E, Ronan K, Gopalakrishnan M, El-Metwally D
J Neonatal Perinatal Med
. 2025 Feb;
18(1):46-51.
PMID: 39973535
Background/ObjectiveNeonatal Opioid Withdrawal Syndrome (NOWS) requires advanced and often prolonged medical care in the neonatal intensive care unit (NICU). We examined the effect of NICU design on treatment and NICU...
2.
Siddiqua T, Schulze K, Hasan S, Ahsan K, Bandyopadhyay S, Zavala E, et al.
BMJ Open
. 2025 Jan;
15(1):e090108.
PMID: 39755576
Introduction: Optimising the micronutrient status of women before and during reproduction confers benefits to them and their offspring. Antenatal multiple micronutrient supplements (MMS), given as a daily tablet with nutrients...
3.
Shah C, Reed R, Simoni-Wastila L, Wastila L, Onukwugha E, Gopalakrishnan M, et al.
Expert Rev Respir Med
. 2024 Dec;
18(12):1113-1120.
PMID: 39718113
Background: Two long-acting muscarinic antagonist inhaler fixed dose combinations (olodaterol/tiotropium (OLO/TIO) and vilanterol/umeclidinium (VI/UMEC)) have once-a-day dosing for managing chronic obstructive pulmonary disease (COPD). This study aimed to compare clinical...
4.
Castillo J, Guerrini V, Quijada D, Karanika S, Neupane P, Urbanowski M, et al.
J Infect Dis
. 2024 Nov;
PMID: 39560474
Tuberculosis (TB) necrotic granulomas contain triglyceride-rich macrophages (foam cells) with reduced antimicrobial functions. We assessed the ability of two compounds to reduce triglyceride content and Mycobacterium tuberculosis (Mtb) burden in...
5.
Roskes L, Chamzas A, Ma B, Medina A, Gopalakrishnan M, Viscardi R, et al.
Pediatr Res
. 2024 Oct;
PMID: 39397156
Objectives: Early exposure to mother's own milk (MOM) promotes intestinal barrier maturation in preterm infants. We hypothesized (1) donor human milk (DHM) supplementation reduces intestinal permeability (IP) similar to exclusive...
6.
Shenkoya B, Gopalakrishnan M, Eke A
CPT Pharmacometrics Syst Pharmacol
. 2024 Oct;
13(11):1939-1952.
PMID: 39380562
Opioid use disorders (OUD) are a major issue in the U.S. Current treatments for pregnant women, like methadone and buprenorphine require daily dosing and have adverse effects. Monthly injectable naltrexone...
7.
Chamzas A, Tellez E, SyBing A, Gobburu J, Gopalakrishnan M
Front Pharmacol
. 2024 Oct;
15:1443988.
PMID: 39364052
Aim: Tacrolimus, an immunosuppressant used to prevent organ rejection in renal transplant patients, exhibits high inter-patient variability, necessitating therapeutic drug monitoring. Early post-transplant tacrolimus exposure in Hispanics is understudied. Although...
8.
Sylvetsky A, Kuttamperoor J, Langevin B, Murphy J, Arcaro K, Smolyak S, et al.
Am J Clin Nutr
. 2024 Aug;
120(4):846-853.
PMID: 39111550
Background: Low-calorie sweetener (LCS) consumption is prevalent among lactating mothers, yet infants' exposure to LCS in human milk is not well-characterized. Objectives: Conduct a pharmacokinetic study of sucralose and acesulfame-potassium...
9.
Wang X, Gopalakrishnan M, Rich B, Gobburu J, Larsen F, Raoufinia A
J Clin Pharmacol
. 2024 Jul;
64(10):1236-1245.
PMID: 38973383
In order to accelerate drug development and avoid unnecessary drug trials in vulnerable pediatric populations, the US Food and Drug Administration (FDA) released a general advice letter to sponsors permitting...
10.
Gopalakrishnan M, Amaria R
Clin Cancer Res
. 2024 May;
30(14):2862-2864.
PMID: 38743418
Leveraging a heterogeneous dataset, a recent article demonstrated the application of pharmacometric modeling to inform the dosing of nivolumab-relatlimab fixed-dose combination in special populations, including adolescents lacking clinical data. The...