Alpha 2.0
Login Register
» Authors » Math P G Leers

Math P G Leers

Explore the profile of Math P G Leers including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 27
Citations 123
Followers 0
Related Specialties
Pathology
Biochemistry
Cell Biology
Top 10 Co-Authors
Frans C S Ramaekers
Stefan G C Mestrum
Anton H N Hopman
Daan J L van Twist
Roosmarie J M Drent
Norbert C J de Wit
Remy L M Mostard
Guy J M Mostard
Martijn D de Kruif
Inge H Y Luu
Published In
Clin Chem Lab Med
Cytometry A
Am J Clin Pathol
Cytometry B Clin Cytom
PLoS One
Affiliations
Soon will be listed here.
Recent Articles
1.
Increased anti-apoptotic (Bcl-2+) and decreased proliferative (Ki-67+) cell fractions during the different maturation stages of bone marrow cell populations in MDS and AML: The potential diagnostic impact of the Bcl-2:Ki-67 ratio
Mestrum S, Schoenmakers T, Wang S, de Wit N, Boonen B, van Hemert W, et al.
Cytometry B Clin Cytom . 2025 Mar; PMID: 40051252
The relationship between apoptosis inhibition and cell proliferation was studied during the maturation stages of erythropoiesis, granulopoiesis, and monopoiesis in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)....
2.
Cell population data in venous thrombo-embolism and erysipelas: a potential diagnostic tool?
Appelboom Y, Leers M, Schoenmakers T, van Twist D
Clin Chem Lab Med . 2024 Oct; 63(4):e108-e112. PMID: 39446414
No abstract available.
3.
MDS and AML show elevated fractions of CD34-positive blast cell populations with a high anti-apoptotic versus proliferation ratio
Mestrum S, Roanalis B, de Wit N, Drent R, Boonen B, van Hemert W, et al.
Leuk Res . 2024 May; 142:107520. PMID: 38776565
This study investigates the intertwined processes of (anti-)apoptosis and cell proliferation in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Utilizing antibodies to Bcl-2 and Ki-67, the CD34-positive blast cell...
4.
Pulmonary embolism in hospitalized COVID-19 patients: Short- and long-term clinical outcomes
Luu I, Buijs J, Krdzalic J, de Kruif M, Mostard G, Ten Cate H, et al.
Thromb Update . 2024 Apr; 12:None. PMID: 38562231
Introduction: Pulmonary embolism (PE) is a frequent complication in COVID-19. However, the influence of PE on the prognosis of COVID-19 remains unclear as previous studies were affected by misclassification bias....
5.
Thyroid and adrenal incidentalomas on chest CT: Prevalence, diagnostic work-up and outcomes in a cohort of COVID-19 suspected patients
Willems J, Tummers-de Lind van Wijngaarden R, Dubelaar I, de Kruif M, Leers M, Luu I, et al.
Eur J Intern Med . 2023 Dec; 123:114-119. PMID: 38123419
Objective: Due to increased use of computed tomography (CT), prevalence of thyroid and adrenal incidentalomas is rising. Yet, previous studies on the outcomes of diagnostic work-up of incidentalomas are subjected...
6.
Impact of the gating strategy for Ki-67 and Bcl-2 on the determination of proliferation and anti-apoptosis data by flow cytometry in non-malignant bone marrow aspirates and aspirates from patients with myeloid malignancies
Mestrum S, Vanblarcum R, de Wit N, Drent R, Boonen B, van Hemert W, et al.
Data Brief . 2023 Jul; 49:109284. PMID: 37409174
This Data in Brief article displays a flow cytometric assay that was used for the acquisition and analyses of proliferative and anti-apoptotic activity in hematopoietic cells. This dataset includes analyses...
7.
Systematic screening versus clinical gestalt in the diagnosis of pulmonary embolism in COVID-19 patients in the emergency department
Luu I, Frijns T, Buijs J, Krdzalic J, de Kruif M, Mostard G, et al.
PLoS One . 2023 Mar; 18(3):e0283459. PMID: 36952456
Background: Diagnosing concomitant pulmonary embolism (PE) in COVID-19 patients remains challenging. As such, PE may be overlooked. We compared the diagnostic yield of systematic PE-screening based on the YEARS-algorithm to...
8.
The Proliferation Index of Erythroid Cells Predicts the Development of Transfusion-dependence in Myelodysplastic Syndrome Patients With Mildly Reduced Hemoglobin Levels at Initial Diagnosis
Mestrum S, de Wit N, Cremers E, Drent R, Ramaekers F, Hopman A, et al.
Hemasphere . 2022 Nov; 6(12):e804. PMID: 36382052
No abstract available.
9.
Flow Cytometric Identification of Hematopoietic and Leukemic Blast Cells for Tailored Clinical Follow-Up of Acute Myeloid Leukemia
Weeda V, Mestrum S, Leers M
Int J Mol Sci . 2022 Sep; 23(18). PMID: 36142442
Acute myeloid leukemia (AML) is a myeloid malignancy that is characterized by the accumulation of leukemic blast cells, which originate from hematopoietic stem cells that have undergone leukemic transformation and/or...
10.
Use of an algorithm based on routine blood laboratory tests to exclude COVID-19 in a screening-setting of healthcare workers
Leers M, Deneer R, Mostard G, Mostard R, Boer A, Scharnhorst V, et al.
PLoS One . 2022 Jun; 17(6):e0270548. PMID: 35763522
Background: COVID-19 is an ongoing pandemic leading to exhaustion of the hospital care system. Our health care system has to deal with a high level of sick leave of health...