Massimo Gennarelli
Overview
Explore the profile of Massimo Gennarelli including associated specialties, affiliations and a list of published articles.
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184
Citations
4536
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Recent Articles
1.
Squassina A, Paribello P, Pinna M, Contu M, Pisanu C, Congiu D, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2025 Feb;
137:111292.
PMID: 39971121
Response to antidepressants (ADs) is highly variable and partly genetically driven, but the utility of pharmacogenetic testing in guiding ADs treatment is still controversial. We conducted a retrospective, naturalistic study...
2.
Galbiati C, Dattilo V, Bortolomasi M, Vitali E, Abate M, Menesello V, et al.
J ECT
. 2025 Jan;
PMID: 39792703
Objectives: Electroconvulsive therapy (ECT) is one of the most effective treatments for treatment-resistant depression (TRD), even though the molecular mechanisms underlying its efficacy remain largely unclear. This study aimed, for...
3.
Meloni A, Paribello P, Pinna M, Contu M, Ardau R, Chillotti C, et al.
Eur Neuropsychopharmacol
. 2024 Nov;
91:37-44.
PMID: 39612728
Mitochondrial dysfunctions have been reported in bipolar disorder (BD), but their role in the etiopathogenesis of BD as well as their implications in modulating response to pharmacological treatments with psychotropic...
4.
Scassellati C, Cattane N, Benedetti F, Borsello T, Cicala G, Gennarelli M, et al.
Brain Behav Immun Health
. 2024 Nov;
42:100886.
PMID: 39583163
About one third of patients suffering from Major Depressive Disorder (MDD) do not respond to any antidepressant medications and 75% experience relapses and general health deterioration. Importantly, inflammation can contribute...
5.
Ravaggi A, Bergamaschi C, Galbiati C, Zanotti L, Fabricio A, Gion M, et al.
Biomedicines
. 2024 Oct;
12(10).
PMID: 39457705
Background/objectives: Endometriosis (END) is a painful gynecological condition. Clinical examination, imaging, and laparoscopy can provide a definitive diagnosis of END. Nonetheless, non-invasive biomarkers could help enhance and streamline the diagnostic...
6.
Squassina A, Pisanu C, Menesello V, Meloni A, Congiu D, Manchia M, et al.
J ECT
. 2024 Aug;
PMID: 39178054
Objectives: In this study, we investigated if changes in leukocyte telomere length (LTL) and mitochondrial DNA copy number (mtDNA-cn), 2 markers of cellular aging, are associated with treatment-resistant depression (TRD)...
7.
Mazzarotto F, Monteleone P, Minelli A, Mattevi S, Cascino G, Rocca P, et al.
Psychiatry Res
. 2024 Aug;
340:116107.
PMID: 39096746
Schizophrenia is a severe psychiatric disorder, associated with a reduction in life expectancy of 15-20 years. Available treatments are at least partially effective in most affected individuals, and personal resources...
8.
Filippini A, Cannone E, Mazziotti V, Carini G, Mutti V, Ravelli C, et al.
Biomolecules
. 2024 Jul;
14(7).
PMID: 39062584
(), a gene mutated in familial and sporadic Parkinson's disease (PD), controls multiple cellular processes important for GLIA physiology. Interestingly, emerging studies report that LRRK2 is highly expressed in oligodendrocyte...
9.
Carvalho Silva R, Martini P, Hohoff C, Mattevi S, Bortolomasi M, Abate M, et al.
Clin Epigenetics
. 2024 Jul;
16(1):93.
PMID: 39020437
Background: Electroconvulsive therapy (ECT) benefits patients with treatment-resistant depression (TRD), but the underlying biological processes are unclear. We conducted an epigenome-wide association study in 32 TRD patients undergoing ECT to...
10.
Lipov A, Jurgens S, Mazzarotto F, Allouba M, Pirruccello J, Aguib Y, et al.
Nat Cardiovasc Res
. 2024 Apr;
2(11):1078-1094.
PMID: 38666070
Discrete categorization of Mendelian disease genes into dominant and recessive models often oversimplifies their underlying genetic architecture. Cardiomyopathies (CMs) are genetic diseases with complex etiologies for which an increasing number...