Masami Nagahama
Overview
Explore the profile of Masami Nagahama including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
656
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Recent Articles
1.
Ogawa A, Izumikawa K, Tate S, Isoyama S, Mori M, Fujiwara K, et al.
Mol Cell
. 2025 Feb;
85(5):894-912.e10.
PMID: 39909041
Impairment of ribosome biogenesis (RiBi) triggered by inhibition of ribosomal RNA (rRNA) synthesis and processing leads to various biological effects. We report that Schlafen 11 (SLFN11) induces TP53-independent apoptosis through...
2.
Hirooka Y, Izumikawa K, Miyao S, Ohga T, Nobe Y, Taoka M, et al.
Biochem Biophys Res Commun
. 2024 Dec;
744:151175.
PMID: 39706051
WD repeat domain 74 (WDR74) is a nucleolar protein involved in the early stages of pre-60S maturation in the ribosome biogenesis pathway. In later stages, WDR74 interacts with MTR4, an...
3.
Komuro R, Honda Y, Yanaizu M, Nagahama M, Kino Y
Cells
. 2023 Feb;
12(4).
PMID: 36831269
Genetic variations of have been implicated as a susceptibility factor of Alzheimer's disease (AD). A polymorphism on exon 2 of , rs12459419, affects the alternative splicing of this exon. The...
4.
Louche A, Blanco A, Lacerda T, Cancade-Veyre L, Lionnet C, Berge C, et al.
Nat Commun
. 2023 Jan;
14(1):102.
PMID: 36609656
The cell nucleus is a primary target for intracellular bacterial pathogens to counteract immune responses and hijack host signalling pathways to cause disease. Here we identify two Brucella abortus effectors,...
5.
Miyao S, Saito K, Oshima R, Kawahara K, Nagahama M
Biochem Biophys Res Commun
. 2022 Nov;
637:203-209.
PMID: 36403484
Ribosome biogenesis proceeds with the successive cleavage and trimming of the large 47S rRNA precursor, where the RNA exosome plays major roles in concert with the Ski2-like RNA helicase, MTR4....
6.
Fujiwara N, Shigemoto M, Hirayama M, Fujita K, Seno S, Matsuda H, et al.
Nucleic Acids Res
. 2022 Jul;
50(15):8779-8806.
PMID: 35902094
Recent in vitro reconstitution analyses have proven that the physical interaction between the exosome core and MTR4 helicase, which promotes the exosome activity, is maintained by either MPP6 or RRP6....
7.
Ishida Y, Miyao S, Saito M, Hiraishi N, Nagahama M
Int J Biochem Cell Biol
. 2021 Jan;
132:105919.
PMID: 33422691
The AAA-ATPase NVL2 associates with an RNA helicase MTR4 and the nuclear RNA exosome in the course of ribosome biogenesis. In our proteomic screen, we had identified a ribosome biogenesis...
8.
Urae S, Harita Y, Udagawa T, Ode K, Nagahama M, Kajiho Y, et al.
J Cell Sci
. 2020 Jun;
133(13).
PMID: 32482797
Cubilin (CUBN) and amnionless (AMN), expressed in kidney and intestine, form a multiligand receptor complex called CUBAM that plays a crucial role in albumin absorption. To date, the mechanism of...
9.
Yamada T, Imamachi N, Imamura K, Taniue K, Kawamura T, Suzuki Y, et al.
Cell Rep
. 2020 May;
31(5):107542.
PMID: 32375027
RNA-binding proteins (RBPs) play a pivotal role in gene expression by modulating the stability of transcripts. However, the identification of degradation target mRNAs of RBPs remains difficult. By the combined...
10.
Sun X, Kawata K, Miki A, Wada Y, Nagahama M, Takaya A, et al.
Biosci Trends
. 2020 May;
14(4):255-262.
PMID: 32350160
Salmonella enterica serovar Typhimurium (Salmonella), a pathogenic bacterium, is a major cause of foodborne diseases worldwide. Salmonella injects multiple virulence factors, called effectors, into cells and causes multiple rearrangements of...