Masako Kohyama
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Explore the profile of Masako Kohyama including associated specialties, affiliations and a list of published articles.
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37
Citations
2973
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Recent Articles
1.
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, et al.
Cell
. 2024 Sep;
187(21):6071-6087.e20.
PMID: 39276775
Major histocompatibility complex class II (MHC-II) is the most significant genetic risk factor for systemic lupus erythematosus (SLE), but the nature of the self-antigens that trigger autoimmunity remains unclear. Unusual...
2.
Naito R, Ohmura K, Higuchi S, Nakai W, Kohyama M, Mimori T, et al.
JCI Insight
. 2023 Jul;
8(16).
PMID: 37432743
The U1RNP complex, Ro/SSA, and La/SSB are major RNA-containing autoantigens. Immune complexes (ICs) composed of RNA-containing autoantigens and autoantibodies are suspected to be involved in the pathogenesis of some systemic...
3.
Kohyama M, Suzuki T, Nakai W, Ono C, Matsuoka S, Iwatani K, et al.
Int Immunol
. 2022 Sep;
35(1):43-52.
PMID: 36053553
Many patients with severe COVID-19 suffer from pneumonia and the elucidation of the mechanisms underlying the development of this severe condition is important. The in vivo function of the ORF8...
4.
Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, et al.
Sci Adv
. 2022 Mar;
8(9):eabj9867.
PMID: 35245125
Specific MHC class II alleles are strongly associated with susceptibility to various autoimmune diseases. Although the primary function of MHC class II molecules is to present peptides to helper T...
5.
Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, et al.
Arthritis Rheumatol
. 2021 Jun;
74(1):105-111.
PMID: 34164946
Objective: Specific HLA class II alleles are associated with susceptibility to systemic lupus erythematosus (SLE). The role of HLA class II molecules in SLE pathogenesis remains unclear, although anti-DNA antibodies...
6.
Liu Y, Soh W, Kishikawa J, Hirose M, Nakayama E, Li S, et al.
Cell
. 2021 Jun;
184(13):3452-3466.e18.
PMID: 34139176
Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike protein domains are largely unknown. Here, we screened...
7.
Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, et al.
Biochem Biophys Res Commun
. 2021 Mar;
548:167-173.
PMID: 33647792
Plasmodium falciparum causes the most severe form of malaria. Acquired immunity against P. falciparum provides insufficient protection even after repeated infections. Therefore, P. falciparum parasites might exploit inhibitory receptors for...
8.
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, et al.
Biochem Biophys Res Commun
. 2020 Nov;
534:680-686.
PMID: 33208230
Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of insulin-producing β cells. The response of autoreactive T cells to β cell antigens plays a central role in...
9.
Soodgupta D, White L, Yang W, Johnston R, Andrews J, Kohyama M, et al.
Cell Rep
. 2019 Oct;
29(4):829-843.e5.
PMID: 31644907
Early B cell development is regulated by stage-specific transcription factors. PU.1, an ETS-family transcription factor, is essential for coordination of early B cell maturation and immunoglobulin gene (Ig) rearrangement. Here...
10.
Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, et al.
Biochem Biophys Res Commun
. 2019 Mar;
511(4):862-868.
PMID: 30850159
HLA class I molecules play a central role in the immune system by presenting peptide antigens to cytotoxic T cells. Although most HLA class I molecules are associated with β2-microglobulin,...