Masahiro Mochizuki
Overview
Explore the profile of Masahiro Mochizuki including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
199
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Recent Articles
1.
Kaminuma E, Baba Y, Mochizuki M, Matsumoto H, Ozaki H, Okayama T, et al.
Genes Genet Syst
. 2020 Mar;
95(1):43-50.
PMID: 32213716
Recently, the prospect of applying machine learning tools for automating the process of annotation analysis of large-scale sequences from next-generation sequencers has raised the interest of researchers. However, finding research...
2.
Chiba S, Ohue M, Gryniukova A, Borysko P, Zozulya S, Yasuo N, et al.
Sci Rep
. 2019 Dec;
9(1):19585.
PMID: 31863054
Potential inhibitors of a target biomolecule, NAD-dependent deacetylase Sirtuin 1, were identified by a contest-based approach, in which participants were asked to propose a prioritized list of 400 compounds from...
3.
Nagatani M, Kodera T, Suzuki D, Igura S, Fukunaga Y, Kanemitsu H, et al.
Exp Anim
. 2019 May;
68(4):471-482.
PMID: 31118345
Biological background data up to 11 weeks of age and tumorigenic susceptibility to xenotransplantation with HeLa cells were compared between severely immuno-deficient NOG and NSG mice. The body weight was...
4.
Mochizuki M, Suzuki S, Yanagisawa K, Ohue M, Akiyama Y
Mol Divers
. 2018 Jul;
23(1):11-18.
PMID: 29971617
Druglikeness is a useful concept for screening drug candidate compounds. We developed QEX, which is a new druglikeness index specific to individual targets. QEX is an improvement of the quantitative...
5.
Kasahara K, Fukunaga Y, Igura S, Andoh R, Saito T, Suzuki I, et al.
J Toxicol Sci
. 2017 Nov;
42(6):689-705.
PMID: 29142168
To obtain background data of NOD/Shi-scid IL-2Rγ (NOG) mice, severely immunedeficient mice, a total of 120 animals were examined at 7, 26 and 52 weeks-old (20 mice/sex/group). The survival rate...
6.
Chiba S, Ishida T, Ikeda K, Mochizuki M, Teramoto R, Taguchi Y, et al.
Sci Rep
. 2017 Sep;
7(1):12038.
PMID: 28931921
We propose a new iterative screening contest method to identify target protein inhibitors. After conducting a compound screening contest in 2014, we report results acquired from a contest held in...
7.
Chiba S, Ikeda K, Ishida T, Gromiha M, Taguchi Y, Iwadate M, et al.
Sci Rep
. 2015 Nov;
5:17209.
PMID: 26607293
A search of broader range of chemical space is important for drug discovery. Different methods of computer-aided drug discovery (CADD) are known to propose compounds in different chemical spaces as...
8.
Ito K, Murakami R, Mochizuki M, Qi H, Shimizu Y, Miura K, et al.
Nucleic Acids Res
. 2012 Aug;
40(20):10521-31.
PMID: 22923517
Peptidyl-tRNA hydrolase (Pth) cleaves the ester bond between the peptide and the tRNA of peptidyl-tRNA molecules, which are produced by aborted translation, to recycle tRNA for further rounds of protein...
9.
Urasoko Y, He X, Masao T, Kinoshita Y, Edamoto H, Hatayama K, et al.
J Am Assoc Lab Anim Sci
. 2012 Jul;
51(2):144-9.
PMID: 22776112
This study measured blood parameters, particularly those related to coagulation, and alterations in the expression levels of blood-coagulation-related genes in lactating Sprague-Dawley rats. The day of delivery was designated as...
10.
Mochizuki M, Kitamyo M, Miyoshi T, Ito K, Uchiumi T
Genes Cells
. 2012 Mar;
17(4):273-84.
PMID: 22390364
Ribosomal protein P0 forms a pentameric complex with two heterodimers of the flexible stalk proteins P1•P2 and plays a role in the functional interaction of eukaryotic ribosomes with translational factors....