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Masafumi Torii

Explore the profile of Masafumi Torii including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Sakairi M, Kogami M, Torii M, Makino M, Kataoka D, Okamoto R, et al.
Chem Pharm Bull (Tokyo) . 2012 Sep; 60(9):1093-5. PMID: 22976315
6-((2-Fluoro-3-(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)propyl)amino)-2,3-dihydro-1H-inden-1-one is a potent drug-like G protein-coupled receptor 119 (GPR119) agonist. It is hoped that this compound would be instrumental in probing the pharmacological potential of GPR119 agonists.
2.
Sakairi M, Kogami M, Torii M, Kataoka H, Fujieda H, Makino M, et al.
Bioorg Med Chem Lett . 2012 Jul; 22(15):5123-8. PMID: 22765901
We disclosed a novel series of G-protein coupled receptor 119 (GPR119) agonists based on a bicyclic amine scaffold. Through the optimization of hit compound 1, we discovered that the basic...
3.
Pilch W, Szygula Z, Klimek A, Palka T, Cison T, Pilch P, et al.
Int J Occup Med Environ Health . 2010 Aug; 23(2):167-74. PMID: 20682487
Objectives: There is little information on lipid metabolism after sauna treatment in the literature. The present research is aimed to determine the influence of sauna baths on fat metabolism in...
4.
Lubkowska A, Szygula Z, Klimek A, Torii M
Eur J Appl Physiol . 2009 Sep; 109(1):67-72. PMID: 19779735
The influence of extremely low temperatures on the human body and physiological reactions are not fully recognized. It has been postulated that cryostimulation could modify immunological reactions, leukocytes mobilization and...