Maryam Ghaderi Najafabadi
Overview
Explore the profile of Maryam Ghaderi Najafabadi including associated specialties, affiliations and a list of published articles.
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6
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94
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Recent Articles
1.
Najafabadi M, Gray G, Kong L, Gupta K, Perera D, Naylor H, et al.
Nat Commun
. 2023 Aug;
14(1):5206.
PMID: 37626143
Germline BRCA2 mutation carriers frequently develop luminal-like breast cancers, but it remains unclear how BRCA2 mutations affect mammary epithelial subpopulations. Here, we report that monoallelic Brca2 mammary organoids subjected to...
2.
Prestel M, Prell-Schicker C, Webb T, Malik R, Lindner B, Ziesch N, et al.
Stroke
. 2019 Sep;
50(10):2651-2660.
PMID: 31500558
Background and Purpose- Genome-wide association studies have identified the (histone deacetylase 9) gene region as a major risk locus for atherosclerotic stroke and coronary artery disease in humans. Previous results...
3.
Aravani D, Morris G, Jones P, Tattersall H, Karamanavi E, Kaiser M, et al.
Circulation
. 2019 Jun;
140(6):500-513.
PMID: 31163988
Background: Genome-wide association studies have identified chromosome 14q32 as a locus for coronary artery disease. The disease-associated variants fall in a hitherto uncharacterized gene called HHIPL1 (hedgehog interacting protein-like 1),...
4.
Jones P, Kaiser M, Najafabadi M, Koplev S, Zhao Y, Douglas G, et al.
Arterioscler Thromb Vasc Biol
. 2018 May;
38(8):1711-1722.
PMID: 29794114
Objective- A large number of genetic loci have been associated with risk of coronary artery disease (CAD) through genome-wide association studies, however, for most loci the underlying biological mechanism is...
5.
Jones P, Kaiser M, Najafabadi M, McVey D, Beveridge A, Schofield C, et al.
J Biol Chem
. 2016 May;
291(31):16318-27.
PMID: 27226629
Genome-wide association studies have to date identified multiple coronary artery disease (CAD)-associated loci; however, for most of these loci the mechanism by which they affect CAD risk is unclear. The...
6.
Pawluczyk I, Najafabadi M, Patel S, Desai P, Vashi D, Saleem M, et al.
Exp Cell Res
. 2013 Nov;
320(2):258-68.
PMID: 24200502
Sialoglycoproteins make a significant contribution to the negative charge of the glomerular anionic glycocalyx-crucial for efficient functioning of the glomerular permselective barrier. Defects in sialylation have serious consequences on podocyte...