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Mary P Leatham-Jensen

Explore the profile of Mary P Leatham-Jensen including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 224
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Recent Articles
1.
Anyetei-Anum C, Leatham-Jensen M, Fox G, Smith B, Chirasani V, Krajewski K, et al.
Genes Dev . 2024 Nov; 38(21-24):1033-1046. PMID: 39562140
Tight control over cell identity gene expression is necessary for proper adult form and function. The opposing activities of Polycomb and trithorax complexes determine the on/off state of cell identity...
2.
Crain A, Nevil M, Leatham-Jensen M, Reeves K, Matera A, McKay D, et al.
Genetics . 2024 Jul; 228(1). PMID: 39039029
Mutating replication-dependent (RD) histone genes is an important tool for understanding chromatin-based epigenetic regulation. Deploying this tool in metazoans is particularly challenging because RD histones in these organisms are typically...
3.
Anyetei-Anum C, Leatham-Jensen M, Fox G, Smith B, Krajewski K, Strahl B, et al.
bioRxiv . 2024 Jul; PMID: 38979215
Tight control over cell identity gene expression is necessary for proper adult form and function. The opposing activities of Polycomb and trithorax complexes determine the ON/OFF state of targets like...
4.
Crain A, Nevil M, Leatham-Jensen M, Reeves K, Matera A, McKay D, et al.
bioRxiv . 2024 May; PMID: 38712307
Mutating replication-dependent (RD) histone genes is an important tool for understanding chromatin-based epigenetic regulation. Deploying this tool in metazoan models is particularly challenging because RD histones in these organisms are...
5.
Salzler H, Vandadi V, McMichael B, Brown J, Boerma S, Leatham-Jensen M, et al.
Sci Adv . 2023 Mar; 9(9):eadf2451. PMID: 36857457
Polycomb complexes regulate cell type-specific gene expression programs through heritable silencing of target genes. Trimethylation of histone H3 lysine 27 (H3K27me3) is essential for this process. Perturbation of H3K36 is...
6.
Leatham-Jensen M, Mokszycki M, Rowley D, Deering R, Camberg J, Sokurenko E, et al.
mSphere . 2016 Jun; 1(1). PMID: 27303698
In the present study, it is shown that although Escherichia coli CFT073, a human uropathogenic (UPEC) strain, grows in liquid glucose M9 minimal medium, it fails to grow on glucose...
7.
Adediran J, Leatham-Jensen M, Mokszycki M, Frimodt-Moller J, Krogfelt K, Kazmierczak K, et al.
Infect Immun . 2014 Jan; 82(2):670-82. PMID: 24478082
Previously we reported that the streptomycin-treated mouse intestine selected for two different Escherichia coli MG1655 mutants with improved colonizing ability: nonmotile E. coli MG1655 flhDC deletion mutants that grew 15%...
8.
Maltby R, Leatham-Jensen M, Gibson T, Cohen P, Conway T
PLoS One . 2013 Jan; 8(1):e53957. PMID: 23349773
Escherichia coli is a single species consisting of many biotypes, some of which are commensal colonizers of mammals and others that cause disease. Humans are colonized on average with five...
9.
Leatham-Jensen M, Frimodt-Moller J, Adediran J, Mokszycki M, Banner M, Caughron J, et al.
Infect Immun . 2012 Mar; 80(5):1716-27. PMID: 22392928
Previously, we reported that the streptomycin-treated mouse intestine selected nonmotile Escherichia coli MG1655 flhDC deletion mutants of E. coli MG1655 with improved colonizing ability that grow 15% faster in vitro...