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Mary N Teruel

Explore the profile of Mary N Teruel including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 1288
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Recent Articles
1.
Ferrick K, Fan Y, Ratnayeke N, Teruel M, Meyer T
bioRxiv . 2024 Oct; PMID: 39416132
Hippo-YAP signaling orchestrates epithelial tissue repair and is therefore an attractive target in regenerative medicine. Yet it is unresolved how YAP integrates with mitogen signaling and contact inhibition to control...
2.
Kudo T, Zhao M, Jeknic S, Kovary K, LaGory E, Covert M, et al.
Cell Syst . 2023 Nov; 14(12):1074-1086.e7. PMID: 37995680
Hypoxia-induced upregulation of HIF1α triggers adipose tissue dysfunction and insulin resistance in obese patients. HIF1α closely interacts with PPARγ, the master regulator of adipocyte differentiation and lipid accumulation, but there...
3.
Bahrami-Nejad Z, Zhang Z, Tholen S, Sharma S, Rabiee A, Zhao M, et al.
PLoS Biol . 2022 Dec; 20(12):e3001900. PMID: 36469503
How progenitor cells can attain a distinct differentiated cell identity is a challenging problem given the fluctuating signaling environment in which cells exist and that critical transcription factors are often...
4.
Ortiz R, Kluwe B, Lazarus S, Teruel M, Joseph J
Trends Endocrinol Metab . 2022 Oct; 33(11):786-797. PMID: 36266164
Stress, in both intrinsic psychosocial and extrinsic physical environmental forms, can impact the development of, and outcomes in, cardiovascular disease (CVD) through allostatic load. Cortisol is a core hormonal mediator...
5.
Zhang Z, Sinha J, Bahrami-Nejad Z, Teruel M
Proc Natl Acad Sci U S A . 2022 Aug; 119(33):e2204470119. PMID: 35939672
Most mammalian cells have an intrinsic circadian clock that coordinates metabolic activity with the daily rest and wake cycle. The circadian clock is known to regulate cell differentiation, but how...
6.
Tholen S, Patel R, Agas A, Kovary K, Rabiee A, Nicholls H, et al.
Cell Rep . 2022 Jun; 39(13):111018. PMID: 35767959
Disruption of circadian glucocorticoid oscillations in Cushing's disease and chronic stress results in obesity and adipocyte hypertrophy, which is believed to be a main source of the harmful effects of...
7.
Zhao M, Rabiee A, Kovary K, Bahrami-Nejad Z, Taylor B, Teruel M
Cell Rep . 2020 Jun; 31(11):107769. PMID: 32553172
Terminal differentiation is essential for the development and maintenance of tissues in all multi-cellular organisms and is associated with permanent exit from the cell cycle. Failure to permanently exit the...
8.
Stowers R, Shcherbina A, Israeli J, Gruber J, Chang J, Nam S, et al.
Nat Biomed Eng . 2019 Jul; 3(12):1009-1019. PMID: 31285581
In breast cancer, the increased stiffness of the extracellular matrix is a key driver of malignancy. Yet little is known about the epigenomic changes that underlie the tumorigenic impact of...
9.
Kovary K, Taylor B, Zhao M, Teruel M
Mol Syst Biol . 2018 May; 14(5):e7997. PMID: 29759982
Due to noise in the synthesis and degradation of proteins, the concentrations of individual vertebrate signaling proteins were estimated to vary with a coefficient of variation (CV) of approximately 25%...
10.
Bahrami-Nejad Z, Zhao M, Tholen S, Hunerdosse D, Tkach K, van Schie S, et al.
Cell Metab . 2018 Apr; 27(4):854-868.e8. PMID: 29617644
Glucocorticoid and other adipogenic hormones are secreted in mammals in circadian oscillations. Loss of this circadian oscillation pattern correlates with obesity in humans, raising the intriguing question of how hormone...