Mary C Perianayagam
Overview
Explore the profile of Mary C Perianayagam including associated specialties, affiliations and a list of published articles.
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24
Citations
670
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Recent Articles
1.
Susantitaphong P, Perianayagam M, Tighiouart H, Liangos O, Bonventre J, Jaber B
Nephron Clin Pract
. 2013 Jun;
123(1-2):67-73.
PMID: 23796916
Background: Tumor necrosis factor-alpha is a proinflammatory cytokine that has been implicated in the pathobiology of acute kidney injury (AKI). Methods: We explored the association of a functional polymorphism in...
2.
Susantitaphong P, Perianayagam M, Kang S, Zhang W, Rao F, OConnor D, et al.
Nephron Clin Pract
. 2013 May;
122(3-4):107-13.
PMID: 23635481
Background: Kallikrein-1 (KLK1) is a highly conserved serine protease that is expressed in the kidney and involved in blood pressure regulation. The activity of this enzyme is diminished in acute...
3.
Susantitaphong P, Perianayagam M, Tighiouart H, Kouznetsov D, Liangos O, Jaber B
Biomarkers
. 2013 Apr;
18(4):331-7.
PMID: 23597157
Context: Urinary α-GST and π-GST are renal tubular leakage markers. Objective: To evaluate the performance characteristics of these markers for the early detection of acute kidney injury (AKI). Materials And...
4.
Perianayagam M, Tighiouart H, Liangos O, Kouznetsov D, Wald R, Rao F, et al.
Kidney Int
. 2012 Jun;
82(8):909-19.
PMID: 22739978
Myeloperoxidase (MPO) is a lysosomal enzyme that may be involved in oxidative stress-mediated kidney injury. Using a two-step approach, we measured the association of four polymorphisms across the length of...
5.
Perianayagam M, Tighiouart H, Nievergelt C, OConnor D, Liangos O, Jaber B
Nephron Extra
. 2012 Apr;
1(1):112-23.
PMID: 22470385
Background: NADPH oxidase is an important enzyme involved in the generation of reactive oxygen species in acute kidney injury (AKI). Its key subunit, p22(phox), is encoded by the highly polymorphic...
6.
Seabra V, Perianayagam M, Tighiouart H, Liangos O, Dos Santos O, Jaber B
Biomarkers
. 2011 Nov;
16(8):709-17.
PMID: 22103586
Context: Urinary α-glutathione S-transferase (α-GST) and π-glutathione S-transferase (π-GST) are promising proximal and distal tubular leakage markers for early detection of acute kidney injury (AKI). Objective: To examine the performance...
7.
Wald R, Liangos O, Perianayagam M, Kolyada A, Herget-Rosenthal S, Mazer C, et al.
Clin J Am Soc Nephrol
. 2010 Jun;
5(8):1373-9.
PMID: 20522534
Background And Objectives: Little is known about the performance of plasma cystatin C (CysC) in patients undergoing cardiopulmonary bypass (CPB) and its utility in the early diagnosis of acute kidney...
8.
Alam A, OConnor D, Perianayagam M, Kolyada A, Chen Y, Rao F, et al.
Nephron Clin Pract
. 2010 Jan;
114(4):c253-9.
PMID: 20090367
Background/aims: The catecholaminergic pathway is important in the physical stress response; however, its role is not well understood in acute kidney injury (AKI). We studied single nucleotide polymorphisms (SNPs) of...
9.
Sun P, Perianayagam M, Jaber B
Kidney Int Suppl
. 2009 Dec;
(114):S20-5.
PMID: 19946323
Chronic inflammation is highly prevalent in patients with chronic kidney disease (CKD), and is associated with increased cardiovascular morbidity and mortality. There are numerous causes of inflammation in CKD, including...
10.
Liangos O, Kolyada A, Tighiouart H, Perianayagam M, Wald R, Jaber B
Nephron Clin Pract
. 2009 Aug;
113(3):c148-54.
PMID: 19672112
Background: Cardiopulmonary bypass (CPB) elicits an inflammatory response mediated partly by neutrophils, which are activated and recruited by interleukin-8 (IL-8). We hypothesized that acute kidney injury (AKI) following CPB might...