Mary C Perianayagam
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Explore the profile of Mary C Perianayagam including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Perianayagam M, Seabra V, Tighiouart H, Liangos O, Jaber B
Am J Kidney Dis
. 2009 Aug;
54(6):1025-33.
PMID: 19660848
Background: Serum cystatin C has emerged as a new and potentially more reliable marker of kidney function. However, its utility and performance in patients with acute kidney injury (AKI), particularly...
12.
Liangos O, Tighiouart H, Perianayagam M, Kolyada A, Han W, Wald R, et al.
Biomarkers
. 2009 Jul;
14(6):423-31.
PMID: 19572801
The purpose of this study was to compare the performance of six candidate urinary biomarkers, kidney injury molecule (KIM)-1, N-acetyl-beta-D-glucosaminidase (NAG), neutrophil gelatinase-associated lipocalin (NGAL), interleukin (IL)-18, cystatin C and...
13.
Sun P, Perianayagam M, Jaber B
J Ren Nutr
. 2009 May;
19(5):432-8.
PMID: 19464926
Objective: There is a growing interest in the potential anti-inflammatory properties of sevelamer hydrochloride, a commonly used phosphate binder for patients with chronic kidney failure. This study explores the hypothesis...
14.
Kolyada A, Tighiouart H, Perianayagam M, Liangos O, Madias N, Jaber B
Kidney Int
. 2009 Mar;
75(12):1322-1329.
PMID: 19279559
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcription factor that mediates many cellular responses to tissue hypoxia, a common feature of acute kidney injury (AKI). Here we studied 241 patients with AKI...
15.
Perianayagam M, Jaber B
Am J Nephrol
. 2008 May;
28(5):802-7.
PMID: 18506105
Background: Sevelamer hydrochloride has been shown to attenuate circulating biomarkers of inflammation in patients with chronic kidney failure. We hypothesize that sevelamer hydrochloride binds bacterial endotoxin (ET) resulting in a...
16.
Perianayagam M, Requintina P, Jaber B, Oxenkrug G
Ann N Y Acad Sci
. 2007 Dec;
1122:253-9.
PMID: 18077578
We recently demonstrated that melatonin, N-acetylserotonin (NAS), and N-acetyldopamine (NAD) attenuate the synthesis of lipopolysaccharide (LPS)-stimulated tumor necrosis factor-alpha (TNF-alpha) and the generation of oxidant radicals. In this study, we...
17.
Liangos O, Perianayagam M, Vaidya V, Han W, Wald R, Tighiouart H, et al.
J Am Soc Nephrol
. 2007 Feb;
18(3):904-12.
PMID: 17267747
The role of urinary biomarkers of kidney injury in the prediction of adverse clinical outcomes in acute renal failure (ARF) has not been well described. The relationship between urinary N-acetyl-beta-(D)-glucosaminidase...
18.
Perianayagam M, Liangos O, Kolyada A, Wald R, MacKinnon R, Li L, et al.
J Am Soc Nephrol
. 2006 Dec;
18(1):255-63.
PMID: 17151330
Reactive oxygen species are important mediators of injury in acute renal failure (ARF). Although polymorphisms that affect key pro- and antioxidant enzymes might alter the susceptibility to oxidative stress-mediated injury,...
19.
Perianayagam M, Oxenkrug G, Jaber B
Ann N Y Acad Sci
. 2005 Sep;
1053:386-93.
PMID: 16179544
Melatonin and N-acetylserotonin (NAS) have antioxidant properties. In the present study, we examined whether melatonin, NAS, and N-acetyldopamine (NAD) have a modulatory effect on tumor necrosis factor-alpha (TNF-alpha) synthesis and...
20.
Rao M, Guo D, Perianayagam M, Tighiouart H, Jaber B, Pereira B, et al.
Am J Kidney Dis
. 2005 Feb;
45(2):324-33.
PMID: 15685511
Background: Interleukin-6 (IL-6) is a mediator and marker of the chronic inflammatory process that is responsible for much of the morbidity and mortality seen in hemodialysis (HD) patients. This study...