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Mary C Halloran

Explore the profile of Mary C Halloran including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 716
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Recent Articles
1.
Haynes E, Burnett K, He J, Jean-Pierre M, Jarzyna M, Eliceiri K, et al.
Elife . 2022 Oct; 11. PMID: 36222498
Development of elaborate and polarized neuronal morphology requires precisely regulated transport of cellular cargos by motor proteins such as kinesin-1. Kinesin-1 has numerous cellular cargos which must be delivered to...
2.
Miller A, Halloran M
Dis Model Mech . 2022 Aug; 15(8). PMID: 36037004
Neurofibromatosis type 1 (NF1) is an autosomal-dominant neurogenetic disorder caused by mutations in the gene neurofibromin 1 (NF1). NF1 predisposes individuals to a variety of symptoms, including peripheral nerve tumors,...
3.
Alassaf M, Halloran M
Elife . 2021 Mar; 10. PMID: 33759764
Endoplasmic reticulum (ER) and mitochondria form close physical associations to facilitate calcium transfer, thereby regulating mitochondrial function. Neurons with high metabolic demands, such as sensory hair cells, are especially dependent...
4.
Kita A, Swider Z, Erofeev I, Halloran M, Goryachev A, Bement W
Mol Biol Cell . 2019 May; 30(14):1645-1654. PMID: 31091161
Mitotic spindles are well known to be assembled from and dependent on microtubules. In contrast, whether actin filaments (F-actin) are required for or are even present in mitotic spindles has...
5.
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran M, et al.
Mech Dev . 2018 May; 152:1-12. PMID: 29777776
Contactin2 (Cntn2)/Transient Axonal Glycoprotein 1 (Tag1), a neural cell adhesion molecule, has established roles in neuronal migration and axon fasciculation in chick and mouse. In zebrafish, antisense morpholino-based studies have...
6.
Lee T, Lee J, Haynes E, Eliceiri K, Halloran M
Front Cell Neurosci . 2017 May; 11:107. PMID: 28473757
Axon growth and branching, and development of neuronal polarity are critically dependent on proper organization and dynamics of the microtubule (MT) cytoskeleton. MTs must organize with correct polarity for delivery...
7.
Ponomareva O, Eliceiri K, Halloran M
Neural Dev . 2016 Jan; 11:2. PMID: 26791407
Background: Charcot-Marie-Tooth2b (CMT2b) is an axonal form of a human neurodegenerative disease that preferentially affects sensory neurons. CMT2b is dominantly inherited and is characterized by unusually early onset, presenting in...
8.
Ponomareva O, Holmen I, Sperry A, Eliceiri K, Halloran M
J Neurosci . 2014 Jul; 34(28):9235-48. PMID: 25009257
Precise regulation of axon branching is crucial for neuronal circuit formation, yet the mechanisms that control branch formation are not well understood. Moreover, the highly complex morphology of neurons makes...
9.
Clay M, Halloran M
Development . 2014 Jun; 141(12):2506-15. PMID: 24917505
The epithelial-to-mesenchymal transition (EMT) is a complex change in cell phenotype that is important for cell migration, morphogenesis and carcinoma metastasis. Loss of epithelial cell adhesion and tight regulation of...
10.
Clay M, Halloran M
Development . 2013 Jun; 140(15):3198-209. PMID: 23804498
Epithelial-to-mesenchymal transitions (EMTs) are crucial for morphogenesis and carcinoma metastasis, yet mechanisms controlling the underlying cell behaviors are poorly understood. RhoGTPase signaling has been implicated in EMT; however, previous studies...