Mary Anne Royal
Overview
Explore the profile of Mary Anne Royal including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
185
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Recent Articles
1.
Laranjeiro R, Harinath G, Hewitt J, Hartman J, Royal M, Meyer J, et al.
Proc Natl Acad Sci U S A
. 2019 Nov;
116(47):23829-23839.
PMID: 31685639
Regular physical exercise is the most efficient and accessible intervention known to promote healthy aging in humans. The molecular and cellular mechanisms that mediate system-wide exercise benefits, however, remain poorly...
2.
Lucanic M, Plummer W, Chen E, Harke J, Foulger A, Onken B, et al.
Nat Commun
. 2017 Feb;
8:14256.
PMID: 28220799
Limiting the debilitating consequences of ageing is a major medical challenge of our time. Robust pharmacological interventions that promote healthy ageing across diverse genetic backgrounds may engage conserved longevity pathways....
3.
Royal D, Bianchi L, Royal M, Lizzio Jr M, Mukherjee G, Nunez Y, et al.
J Biol Chem
. 2005 Oct;
280(51):41976-86.
PMID: 16239217
DEG/ENaC channel subunits are two transmembrane domain proteins that assemble into heteromeric complexes to perform diverse biological functions that include sensory perception, electrolyte balance, and synaptic plasticity. Hyperactivation of neuronally...
4.
Bianchi L, Gerstbrein B, Frokjaer-Jensen C, Royal D, Mukherjee G, Royal M, et al.
Nat Neurosci
. 2004 Nov;
7(12):1337-44.
PMID: 15543143
Hyperactivation of the Caenorhabditis elegans MEC-4 Na(+) channel of the DEG/ENaC superfamily (MEC-4(d)) induces neuronal necrosis through an increase in intracellular Ca(2+) and calpain activation. How exacerbated Na(+) channel activity...