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Martyna Modrzejewska

Explore the profile of Martyna Modrzejewska including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 132
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Recent Articles
1.
Pawluk H, Tafelska-Kaczmarek A, Soponska M, Porzych M, Modrzejewska M, Pawluk M, et al.
Biomolecules . 2024 Sep; 14(9). PMID: 39334896
Stroke is the second leading cause of death worldwide, and its incidence is rising rapidly. Acute ischemic stroke is a subtype of stroke that accounts for the majority of stroke...
2.
Sutkowy P, Modrzejewska M, Porzych M, Wozniak A
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000024
The significance of physical activity in sports is self-evident. However, its importance is becoming increasingly apparent in the context of public health. The constant desire to improve health and performance...
3.
Wroblewska J, Wroblewski M, Holynska-Iwan I, Modrzejewska M, Nuszkiewicz J, Wroblewska W, et al.
Antioxidants (Basel) . 2023 Jul; 12(7). PMID: 37507865
During inflammatory processes, immunocompetent cells are exposed to substantial amounts of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that is an important and ubiquitous antioxidant molecule produced...
4.
Kupczyk D, Studzinska R, Kolodziejska R, Baumgart S, Modrzejewska M, Wozniak A
J Clin Med . 2022 Oct; 11(20). PMID: 36294507
Glucocorticoids (GCs) belong to the group of steroid hormones. Their representative in humans is cortisol. GCs are involved in most physiological processes of the body and play a significant role...
5.
Sutkowy P, Wroblewska J, Wroblewski M, Nuszkiewicz J, Modrzejewska M, Wozniak A
J Clin Med . 2022 Aug; 11(16). PMID: 36013072
Cardiovascular diseases constitute the most important public health problem in the world. They are characterized by inflammation and oxidative stress in the heart and blood. Physical activity is recognized as...
6.
Rozalski R, Gackowski D, Skalska-Bugala A, Starczak M, Siomek-Gorecka A, Zarakowska E, et al.
Sci Rep . 2021 Nov; 11(1):21345. PMID: 34725426
The active DNA demethylation process may be linked to aberrant methylation and may be involved in leukemogenesis. We investigated the role of epigenetic DNA modifications in childhood acute lymphoblastic leukemia...
7.
Artemov A, Zhenilo S, Kaplun D, Starshin A, Sokolov A, Mazur A, et al.
Epigenetics . 2021 Sep; 17(8):894-905. PMID: 34494499
Hypermethylation of tumour suppressors and other aberrations of DNA methylation in tumours play a significant role in cancer progression. DNA methylation can be affected by various environmental conditions, including hypoxia....
8.
Modrzejewska M, Gawronski M, Gackowski D
Anal Biochem . 2021 Feb; 618:114129. PMID: 33556332
Our first objective was to develop an approach useful for reliable normalization of 2-hydroxyglutarate (2-HG) intracellular levels. The second objective was to use our data normalization strategy to verify previously...
9.
Starczak M, Zarakowska E, Modrzejewska M, Dziaman T, Szpila A, Linowiecka K, et al.
J Transl Med . 2018 Jul; 16(1):204. PMID: 30029654
Background: A characteristic feature of malignant cells, such as colorectal cancer cells, is a profound decrease in the level of 5-hydroxymethylcytosine, a product of 5-methylcytosine oxidation by TET enzymes. Recent...
10.
Dziaman T, Gackowski D, Guz J, Linowiecka K, Bodnar M, Starczak M, et al.
Clin Epigenetics . 2018 Jun; 10:72. PMID: 29875879
Background: Active demethylation of 5-methyl-2'-deoxycytidine (5-mdC) in DNA occurs by oxidation to 5-(hydroxymethyl)-2'-deoxycytidine (5-hmdC) and further oxidation to 5-formyl-2'-deoxycytidine (5-fdC) and 5-carboxy-2'-deoxycytidine (5-cadC), and is carried out by enzymes of...