Martin Wienisch
Overview
Explore the profile of Martin Wienisch including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
489
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0
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Recent Articles
1.
Ryu J, Statz J, Chan W, Oyama K, Custer M, Wienisch M, et al.
Cells
. 2024 May;
13(10.
PMID: 38786052
Huntington's disease (HD) arises from expanded CAG repeats in exon 1 of the () gene. The resultant misfolded HTT protein accumulates within neuronal cells, negatively impacting their function and survival....
2.
Krienen F, Levandowski K, Zaniewski H, Del Rosario R, Schroeder M, Goldman M, et al.
Sci Adv
. 2023 Oct;
9(41):eadk3986.
PMID: 37824615
The mammalian brain is composed of many brain structures, each with its own ontogenetic and developmental history. We used single-nucleus RNA sequencing to sample over 2.4 million brain cells across...
3.
Colvin S, Lea N, Zhang Q, Wienisch M, Kaiser T, Aida T, et al.
eNeuro
. 2022 Aug;
9(5).
PMID: 35977823
Fragile X syndrome (FXS) is a leading monogenic cause of intellectual disability and autism spectrum disorders, spurring decades of intense research and a multitude of mouse models. So far, these...
4.
Wilde J, Aida T, Del Rosario R, Kaiser T, Qi P, Wienisch M, et al.
Cell
. 2021 May;
184(12):3267-3280.e18.
PMID: 34043941
Searching for factors to improve knockin efficiency for therapeutic applications, biotechnology, and generation of non-human primate models of disease, we found that the strand exchange protein RAD51 can significantly increase...
5.
6.
Wallace J, Wienisch M, Murthy V
Neuron
. 2017 Oct;
96(4):883-896.e7.
PMID: 29056299
New neurons appear only in a few regions of the adult mammalian brain and become integrated into existing circuits. Little is known about the functional development of individual neurons in ...
7.
Wienisch M, Murthy V
Sci Rep
. 2016 Jul;
6:29308.
PMID: 27388949
Information processing in early sensory regions is modulated by a diverse range of inhibitory interneurons. We sought to elucidate the role of olfactory bulb interneurons called granule cells (GCs) in...
8.
Blauvelt D, Sato T, Wienisch M, Knopfel T, Murthy V
Front Neural Circuits
. 2013 Apr;
7:46.
PMID: 23543674
The acquisition of olfactory information and its early processing in mammals are modulated by brain states through sniffing behavior and neural feedback. We imaged the spatiotemporal pattern of odor-evoked activity...
9.
Kononenko N, Diril M, Puchkov D, Kintscher M, Koo S, Pfuhl G, et al.
Proc Natl Acad Sci U S A
. 2013 Jan;
110(6):E526-35.
PMID: 23345427
Neurotransmission depends on the exocytic fusion of synaptic vesicles (SVs) and their subsequent reformation either by clathrin-mediated endocytosis or budding from bulk endosomes. How synapses are able to rapidly recycle...
10.
Hagiwara A, Pal S, Sato T, Wienisch M, Murthy V
Front Neural Circuits
. 2012 Apr;
6:18.
PMID: 22529781
Primary olfactory cortical areas receive direct input from the olfactory bulb, but also have extensive associational connections that have been mainly studied with classical anatomical methods. Here, we shed light...