Martin Pfaffendorf
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Explore the profile of Martin Pfaffendorf including associated specialties, affiliations and a list of published articles.
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24
Citations
72
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Recent Articles
1.
Schimmel K, Bennink R, de Bruin K, Leen R, Sand K, van den Hoff M, et al.
Arch Toxicol
. 2005 May;
79(5):268-76.
PMID: 15902424
The experimental anticancer drug cyclopentenyl cytosine (CPEC) was associated with cardiotoxicity in a phase I study. The aim of the present study was twofold; first we investigated whether the observed...
2.
Nap A, Mathy M, Balt J, Pfaffendorf M, Van Zwieten P
Fundam Clin Pharmacol
. 2004 May;
18(3):309-19.
PMID: 15147282
Sympathetic neurotransmission in tissues with intact sympathetic nerve arborization is extensively dependent on calcium influx via N-type calcium-channels. It was the objective of the present study to assess and compare...
3.
Nap A, Mathy M, Pfaffendorf M, Van Zwieten P
J Cardiovasc Pharmacol
. 2004 Apr;
43(3):432-9.
PMID: 15076228
The present study was designed to investigate the influence of maturation (young versus adult) on the angiotensin II-mediated facilitation of sympathetic nerve traffic (prejunctional AT1-receptor) as well as on the...
4.
Streefkerk J, Balt J, van Montfrans G, van Lieshout J, Pfaffendorf M, Van Zwieten P
J Hypertens
. 2004 Apr;
22(3):551-5.
PMID: 15076161
Objective: It was the objective of this study to investigate whether a facilitatory role of vasopressin (AVP) on sympathetic nerve activity can be demonstrated in humans at the peripheral level....
5.
Streefkerk J, Hoogaars W, Christoffels V, Sand C, Pfaffendorf M, Peters S, et al.
Fundam Clin Pharmacol
. 2004 Jan;
18(1):45-50.
PMID: 14748753
To investigate the involvement of the mitogen-activated protein kinase (MAPK) family of extracellular signal-regulated kinase (ERK) 1 and 2 (MAPKerk1/2) in the vasopressin-mediated vasoconstriction in the rat aorta. Vasopressin-induced vasoconstriction...
6.
Knol R, Doornbos T, van den Bos J, de Bruin K, Pfaffendorf M, Aanhaanen W, et al.
Nucl Med Biol
. 2004 Jan;
31(1):111-23.
PMID: 14741576
A series of iodinated thiadiazolyltetrahydro-1-methyl-pyridine (TZTP) compounds was synthesized and evaluated in vitro and in vivo as potential radioligands for imaging of the muscarinic M2 receptor subtype with SPET. One...
7.
Nap A, Belterman C, Mathy M, Balt J, Pfaffendorf M, Van Zwieten P
J Renin Angiotensin Aldosterone Syst
. 2003 Dec;
4(4):220-7.
PMID: 14689369
Congestive heart failure (CHF) is characterised by activation of the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system (SNS). Both systems are known to interact and to potentiate each other...
8.
Nap A, Balt J, Mathy M, Pfaffendorf M, Van Zwieten P
J Cardiovasc Pharmacol
. 2003 Dec;
43(1):14-20.
PMID: 14668562
Angiotensin (AT) II is known to enhance responses to electrical field stimulation (EFS) via AT1 receptors located on sympathetic nerve terminals. Differences in potency exist between AT1 receptor antagonists regarding...
9.
Streefkerk J, Pfaffendorf M, Van Zwieten P
J Cardiovasc Pharmacol
. 2003 Nov;
42(6):703-9.
PMID: 14639090
Objectives: To identify and quantify the stimulatory and inhibitory activity of endothelial factors on Arginine vasopressin (AVP)-induced contractions. Methods: In a standard organ bath set-up for isometric force recording, rabbit...
10.
Nap A, Balt J, Pfaffendorf M, Van Zwieten P
J Renin Angiotensin Aldosterone Syst
. 2003 Jun;
4(2):100-5.
PMID: 12806592
Angiotensin II (Ang II) enhances sympathetic neurotransmission via AT(1)-receptors located on sympathetic nerve terminals. We recently demonstrated that inhibition of Ang II-mediated facilitation in the pithed rat by irbesartan resulted...