Martin Norin
Overview
Explore the profile of Martin Norin including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
121
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0
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Recent Articles
1.
Hojjat-Farsangi M, Moshfegh A, Schultz J, Norin M, Olin T, Osterborg A, et al.
Handb Exp Pharmacol
. 2021 Sep;
269:75-99.
PMID: 34490515
Receptor tyrosine kinases (RTKs) are frequently dysregulated in malignancies and important for the malignant characteristics of tumor cells. RTKs are attractive structures for drug targeting of cancer. The RTK ROR1...
2.
Gustafsson N, Farnegardh K, Bonagas N, Ninou A, Groth P, Wiita E, et al.
Nat Commun
. 2018 Sep;
9(1):3872.
PMID: 30250201
The glycolytic PFKFB3 enzyme is widely overexpressed in cancer cells and an emerging anti-cancer target. Here, we identify PFKFB3 as a critical factor in homologous recombination (HR) repair of DNA...
3.
Millar D, Lewis M, Horan M, Newsway V, Aled Rees D, Easter T, et al.
Mol Cell Endocrinol
. 2008 Oct;
296(1-2):18-25.
PMID: 18950677
Among Europeans, functionally significant GH1 gene variants occur not only in individuals with idiopathic growth hormone (GH) deficiency and/or short stature but also fairly frequently in the general population. To...
4.
Lewis M, Horan M, Millar D, Newsway V, Easter T, Fryklund L, et al.
J Clin Endocrinol Metab
. 2004 Mar;
89(3):1068-75.
PMID: 15001589
The pituitary-expressed GH1 gene was screened for mutation in a group of 74 children with familial short stature. Two novel mutations were identified: an Ile179Met substitution and a -360A-->G promoter...
5.
Millar D, Lewis M, Horan M, Newsway V, Easter T, Gregory J, et al.
Hum Mutat
. 2003 Mar;
21(4):424-40.
PMID: 12655557
Subtle mutations in the growth hormone 1 (GH1) gene have been regarded as a comparatively rare cause of short stature. Such lesions were sought in a group of 41 individuals...
6.
Norin M, Sundstrom M
Farmaco
. 2002 Dec;
57(11):947-51.
PMID: 12484544
The genomics efforts have identified a large number of novel genes and thus provided a pool of interesting but not functionally characterized target proteins. It has been suggested that structural...
7.
Norin M, Sundstrom M
Trends Biotechnol
. 2002 Jan;
20(2):79-84.
PMID: 11814598
The major challenge for post-genomic research is to functionally assign and validate a large number of novel target genes and their corresponding proteins. Functional genomics approaches have, therefore, gained considerable...