Martin N Cheramie
Overview
Explore the profile of Martin N Cheramie including associated specialties, affiliations and a list of published articles.
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7
Citations
99
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Recent Articles
1.
Phelps G, Cheramie M, Fernando D, Selchow P, Meyer C, Waidyarachchi S, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(2):e2314101120.
PMID: 38165935
(), a nontuberculous mycobacterial (NTM) species, is an emerging pathogen with high intrinsic drug resistance. Current standard-of-care therapy results in poor outcomes, demonstrating the urgent need to develop effective antimycobacterial...
2.
DeJarnette C, Meyer C, Jenner A, Butts A, Peters T, Cheramie M, et al.
ACS Infect Dis
. 2021 Nov;
7(12):3210-3223.
PMID: 34786940
Fungal fatty acid (FA) synthase and desaturase enzymes are essential for the growth and virulence of human fungal pathogens. These enzymes are structurally distinct from their mammalian counterparts, making them...
3.
Griffith E, Zhao Y, Singh A, Conlon B, Tangallapally R, Shadrick W, et al.
ACS Infect Dis
. 2019 Oct;
5(11):1915-1925.
PMID: 31588734
Acyldepsipeptides are a unique class of antibiotics that act via allosterically dysregulated activation of the bacterial caseinolytic protease (ClpP). The ability of ClpP activators to kill nongrowing bacteria represents a...
4.
Cherian P, Cheramie M, Marreddy R, Fernando D, Hurdle J, Lee R
Bioorg Med Chem Lett
. 2018 Aug;
28(18):3105-3112.
PMID: 30097368
β-Lactams are the most important class of antibiotics, for which the emergence of resistance threatens their utility. As such, we explored the extent to which the tetramic acid motif, frequently...
5.
Cherian P, Deshpande A, Cheramie M, Bruhn D, Hurdle J, Lee R
J Antibiot (Tokyo)
. 2016 May;
70(1):65-72.
PMID: 27189120
Exploiting iron-uptake pathways by conjugating β-lactam antibiotics with iron-chelators, such as catechol and hydroxamic acid is a proven strategy to overcome permeability-related resistance in Gram-negative bacteria. As naturally occurring iron-chelating...
6.
Pettersson B, Das S, Krishna Behra P, Jordan H, Ramesh M, Mallick A, et al.
PLoS One
. 2015 Oct;
10(10):e0139823.
PMID: 26445268
We have used RNASeq and qRT-PCR to study mRNA levels for all σ-factors in different Mycobacterium marinum strains under various growth and stress conditions. We also studied their levels in...
7.
Leung W, Shaffer C, Reed L, Smith S, Barshop W, Dirkes W, et al.
G3 (Bethesda)
. 2015 Mar;
5(5):719-40.
PMID: 25740935
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties...