Martin Klumpp
Overview
Explore the profile of Martin Klumpp including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
248
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Klink T, Staeben M, Twesten K, Kopp A, Kumar M, Dunn R, et al.
J Biomol Screen
. 2011 Sep;
17(1):59-70.
PMID: 21956169
Methylation is a ubiquitous covalent modification used to control the function of diverse biomolecules including hormones, neurotransmitters, xenobiotics, proteins, nucleic acids, and lipids. Histone methyltransferases (HMTs) are currently of high...
12.
Habig M, Blechschmidt A, Dressler S, Hess B, Patel V, Billich A, et al.
J Biomol Screen
. 2009 May;
14(6):679-89.
PMID: 19470716
High-throughput screening often identifies not only specific, stoichiometrically binding inhibitors but also undesired compounds that unspecifically interfere with the targeted activity by nonstoichiometrically binding, unfolding, and/or inactivating proteins. In this...
13.
Recht M, Torres F, De Bruyker D, Bell A, Klumpp M, Bruce R
Anal Biochem
. 2009 Mar;
388(2):204-12.
PMID: 19250916
Enthalpy arrays enable label-free, solution-based calorimetric detection of molecular interactions in a 96-detector array format. Compared with conventional calorimetry, enthalpy arrays achieve a significant reduction of sample volume and measurement...
14.
Graf C, Klumpp M, Habig M, Rovina P, Billich A, Baumruker T, et al.
Mol Pharmacol
. 2008 Jul;
74(4):925-32.
PMID: 18612076
Ceramide kinase (CerK) produces the bioactive lipid ceramide-1-phosphate (C1P) and appears as a key enzyme for controlling ceramide levels. In this study, we discovered and characterized adamantane-1-carboxylic acid (2-benzoylamino-benzothiazol-6-yl)amide (NVP-231),...
15.
Klumpp M, Boettcher A, Becker D, Meder G, Blank J, Leder L, et al.
J Biomol Screen
. 2006 Jun;
11(6):617-33.
PMID: 16760365
This article discusses the development of homogeneous, miniaturized assays for the identification of novel kinase inhibitors from very large compound collections. In particular, the suitability of time-resolved fluorescence resonance energy...
16.
Wolcke J, Reimann M, Klumpp M, Gohler T, Kim E, Deppert W
J Biol Chem
. 2003 Jun;
278(35):32587-95.
PMID: 12813031
The concept that the tumor suppressor p53 is a latent DNA-binding protein that must become activated for sequence-specific DNA binding recently has been challenged, although the "activation" phenomenon has been...